Your browser doesn't support javascript.
loading
Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarIDHy): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study.
Abou-Alfa, Ghassan K; Macarulla, Teresa; Javle, Milind M; Kelley, Robin K; Lubner, Sam J; Adeva, Jorge; Cleary, James M; Catenacci, Daniel V; Borad, Mitesh J; Bridgewater, John; Harris, William P; Murphy, Adrian G; Oh, Do-Youn; Whisenant, Jonathan; Lowery, Maeve A; Goyal, Lipika; Shroff, Rachna T; El-Khoueiry, Anthony B; Fan, Bin; Wu, Bin; Chamberlain, Christina X; Jiang, Liewen; Gliser, Camelia; Pandya, Shuchi S; Valle, Juan W; Zhu, Andrew X.
Afiliação
  • Abou-Alfa GK; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Weill Medical College at Cornell University, New York, NY, USA.
  • Macarulla T; Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.
  • Javle MM; Department of Gastrointestinal Medical Oncology, MD Anderson Cancer Center, Houston, TX, USA.
  • Kelley RK; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.
  • Lubner SJ; Department of Medicine, University of Wisconsin Carbone Cancer Center, Madison, WI, USA.
  • Adeva J; Department of Medical Oncology, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Cleary JM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Catenacci DV; Department of Medicine, University of Chicago Medical Center, Chicago, IL, USA.
  • Borad MJ; Department of Hematology-Oncology, Mayo Clinic Cancer Center, Phoenix, AZ, USA.
  • Bridgewater J; Department of Medical Oncology, UCL Cancer Institute, London, UK.
  • Harris WP; Department of Medicine, University of Washington, Seattle, WA, USA.
  • Murphy AG; Department of Oncology-Gastrointestinal Cancer, Johns Hopkins University, Baltimore, MD, USA.
  • Oh DY; Department of Internal Medicine, Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
  • Whisenant J; Medical Oncology and Hematology, Utah Cancer Specialists, Salt Lake City, UT, USA.
  • Lowery MA; Trinity St James Cancer Institute, Trinity College Dublin, Dublin, Ireland.
  • Goyal L; Department of Medicine, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.
  • Shroff RT; Department of Medicine, University of Arizona Cancer Center, Tucson, AZ, USA.
  • El-Khoueiry AB; Department of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA.
  • Fan B; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Wu B; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Chamberlain CX; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Jiang L; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Gliser C; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Pandya SS; Agios Pharmaceuticals, Cambridge, MA, USA.
  • Valle JW; Division of Cancer Sciences, University of Manchester, Manchester, UK; Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
  • Zhu AX; Department of Medicine, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA; Jiahui International Cancer Center, Jiahui Health, Shanghai, China. Electronic address: azhu@mgh.harvard.edu.
Lancet Oncol ; 21(6): 796-807, 2020 06.
Article em En | MEDLINE | ID: mdl-32416072
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Piridinas / Neoplasias dos Ductos Biliares / Colangiocarcinoma / Resistencia a Medicamentos Antineoplásicos / Inibidores Enzimáticos / Glicina / Isocitrato Desidrogenase / Mutação / Antineoplásicos Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do norte / Asia / Europa Idioma: En Revista: Lancet Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Piridinas / Neoplasias dos Ductos Biliares / Colangiocarcinoma / Resistencia a Medicamentos Antineoplásicos / Inibidores Enzimáticos / Glicina / Isocitrato Desidrogenase / Mutação / Antineoplásicos Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do norte / Asia / Europa Idioma: En Revista: Lancet Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos