Curcumin potentiates laryngeal squamous carcinoma radiosensitivity via NF-&#922;B inhibition by suppressing IKKÎ³ expression.

Deng, Xin-Zhou; Geng, Shan-Shan; Luo, Ming; Chai, Jing-Jing; Xu, Ying; Chen, Chun-Li; Qiu, Li; Ke, Qing; Duan, Qi-Wen; Song, Shi-Mao; Shen, Li; Luo, Zhi-Guo

Curcumin potentiates laryngeal squamous carcinoma radiosensitivity via NF-ΚB inhibition by suppressing IKKÎ³ expression.

Deng, Xin-Zhou; Geng, Shan-Shan; Luo, Ming; Chai, Jing-Jing; Xu, Ying; Chen, Chun-Li; Qiu, Li; Ke, Qing; Duan, Qi-Wen; Song, Shi-Mao; Shen, Li; Luo, Zhi-Guo.

Afiliação

Deng XZ; Department of Clinical Oncology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, PR China.
Geng SS; HubeiKey Laboratory of Embryonic Stem Cell Research, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, PR China.
Luo M; Department of Clinical Oncology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, PR China.
Chai JJ; Postgraduate Training Base, Shiyan Taihe Hospital, Jinzhou Medical University, Shiyan, Hubei, PR China.
Xu Y; Department of Clinical Oncology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, PR China.
Chen CL; Department of Clinical Oncology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, PR China.
Qiu L; Department of Clinical Oncology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, PR China.
Ke Q; Department of Clinical Oncology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, PR China.
Duan QW; Department of Clinical Oncology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, PR China.
Song SM; Department of Clinical Oncology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, PR China.
Shen L; Department of Clinical Oncology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, PR China.
Luo ZG; Department of Clinical Oncology, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei, PR China.

J Recept Signal Transduct Res ; 40(6): 541-549, 2020 Dec.

Article em En | MEDLINE | ID: mdl-32515250

Assuntos

Carcinoma de Células Escamosas/radioterapia; Curcumina/farmacologia; Quinase I-kappa B/antagonistas & inibidores; Neoplasias Laríngeas/radioterapia; NF-kappa B/antagonistas & inibidores; Tolerância a Radiação/efeitos dos fármacos; Radiossensibilizantes/farmacologia; Antineoplásicos/farmacologia; Apoptose; Biomarcadores Tumorais/genética; Biomarcadores Tumorais/metabolismo; Carcinoma de Células Escamosas/tratamento farmacológico; Carcinoma de Células Escamosas/metabolismo; Carcinoma de Células Escamosas/patologia; Proliferação de Células; Regulação Neoplásica da Expressão Gênica; Humanos; Neoplasias Laríngeas/tratamento farmacológico; Neoplasias Laríngeas/metabolismo; Neoplasias Laríngeas/patologia; Fosforilação; Transdução de Sinais; Células Tumorais Cultivadas

Palavras-chave

Curcumin; IKKÎ³; NF-κB; laryngeal squamous carcinoma; radiosensitivity

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos / Tratamento / Radioterapia Base de dados: MEDLINE Assunto principal: Radiossensibilizantes / Tolerância a Radiação / Carcinoma de Células Escamosas / Neoplasias Laríngeas / NF-kappa B / Curcumina / Quinase I-kappa B Limite: Humans Idioma: En Revista: J Recept Signal Transduct Res Assunto da revista: BIOQUIMICA / FISIOLOGIA Ano de publicação: 2020 Tipo de documento: Article

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