Non-specific protection from respiratory tract infections in cattle generated by intranasal administration of an innate immune stimulant.

Wheat, William; Chow, Lyndah; Rozo, Vanessa; Herman, Julia; Still Brooks, Kelly; Colbath, Aimee; Hunter, Randy; Dow, Steven

Wheat, William; Chow, Lyndah; Rozo, Vanessa; Herman, Julia; Still Brooks, Kelly; Colbath, Aimee; Hunter, Randy; Dow, Steven.

Afiliação

Wheat W; Department of Clinical Sciences, From the Center for Immune and Regenerative Medicine, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, Colorado, United States of America.
Chow L; Department of Clinical Sciences, From the Center for Immune and Regenerative Medicine, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, Colorado, United States of America.
Rozo V; Department of Clinical Sciences, From the Center for Immune and Regenerative Medicine, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, Colorado, United States of America.
Herman J; Department of Clinical Sciences, From the Center for Immune and Regenerative Medicine, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, Colorado, United States of America.
Still Brooks K; Department of Clinical Sciences, From the Center for Immune and Regenerative Medicine, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, Colorado, United States of America.
Colbath A; Department of Clinical Sciences, From the Center for Immune and Regenerative Medicine, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, Colorado, United States of America.
Hunter R; Hunter Cattle Company, Wheatland, Wyoming, United States of America.
Dow S; Department of Clinical Sciences, From the Center for Immune and Regenerative Medicine, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, Colorado, United States of America.

PLoS One ; 15(6): e0235422, 2020.

Article em En | MEDLINE | ID: mdl-32584899

Assuntos

Complexo Respiratório Bovino/patologia; Imunidade Inata/efeitos dos fármacos; Medicamentos para o Sistema Respiratório/farmacologia; Administração Intranasal; Animais; Complexo Respiratório Bovino/tratamento farmacológico; Complexo Respiratório Bovino/mortalidade; Bovinos; Antígenos de Histocompatibilidade Classe II/metabolismo; Interferon gama/genética; Interferon gama/metabolismo; Interleucina-6/genética; Interleucina-6/metabolismo; Leucócitos Mononucleares/citologia; Leucócitos Mononucleares/metabolismo; Lipossomos/química; Macrófagos/citologia; Macrófagos/efeitos dos fármacos; Macrófagos/imunologia; Macrófagos/metabolismo; Mannheimia haemolytica/isolamento & purificação; Mannheimia haemolytica/patogenicidade; Nasofaringe/metabolismo; Nasofaringe/microbiologia; Óxido Nítrico/metabolismo; Fagocitose; Medicamentos para o Sistema Respiratório/uso terapêutico; Taxa de Sobrevida; Receptor 3 Toll-Like/agonistas; Receptor Toll-Like 9/agonistas; Regulação para Cima/efeitos dos fármacos

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Medicamentos para o Sistema Respiratório / Complexo Respiratório Bovino / Imunidade Inata Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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