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Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone.
Yan, Pengrong; Patel, Hardik J; Sharma, Sahil; Corben, Adriana; Wang, Tai; Panchal, Palak; Yang, Chenghua; Sun, Weilin; Araujo, Thais L; Rodina, Anna; Joshi, Suhasini; Robzyk, Kenneth; Gandu, Srinivasa; White, Julie R; de Stanchina, Elisa; Modi, Shanu; Janjigian, Yelena Y; Hill, Elizabeth G; Liu, Bei; Erdjument-Bromage, Hediye; Neubert, Thomas A; Que, Nanette L S; Li, Zihai; Gewirth, Daniel T; Taldone, Tony; Chiosis, Gabriela.
Afiliação
  • Yan P; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Patel HJ; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Sharma S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Corben A; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Currently at Mount Sinai Hospital, New York, NY 10029, USA.
  • Wang T; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Panchal P; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Yang C; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Currently at Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China.
  • Sun W; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Araujo TL; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Rodina A; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Joshi S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Robzyk K; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Gandu S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • White JR; Comparative Pathology Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • de Stanchina E; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Modi S; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Janjigian YY; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Hill EG; Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA.
  • Liu B; Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, OH 43210, USA.
  • Erdjument-Bromage H; Department of Cell Biology and Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY 10016, USA.
  • Neubert TA; Department of Cell Biology and Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY 10016, USA.
  • Que NLS; Hauptman-Woodward Medical Research Institute, Buffalo, NY 14203, USA.
  • Li Z; Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, OH 43210, USA.
  • Gewirth DT; Hauptman-Woodward Medical Research Institute, Buffalo, NY 14203, USA.
  • Taldone T; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Chiosis G; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address: chiosisg@mskcc.org.
Cell Rep ; 31(13): 107840, 2020 06 30.
Article em En | MEDLINE | ID: mdl-32610141

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Chaperonas Moleculares / Proteínas de Choque Térmico HSP70 / Proteínas de Membrana Limite: Animals / Humans Idioma: En Revista: Cell Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Chaperonas Moleculares / Proteínas de Choque Térmico HSP70 / Proteínas de Membrana Limite: Animals / Humans Idioma: En Revista: Cell Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos