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Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia.
De Biasi, Sara; Meschiari, Marianna; Gibellini, Lara; Bellinazzi, Caterina; Borella, Rebecca; Fidanza, Lucia; Gozzi, Licia; Iannone, Anna; Lo Tartaro, Domenico; Mattioli, Marco; Paolini, Annamaria; Menozzi, Marianna; Milic, Jovana; Franceschi, Giacomo; Fantini, Riccardo; Tonelli, Roberto; Sita, Marco; Sarti, Mario; Trenti, Tommaso; Brugioni, Lucio; Cicchetti, Luca; Facchinetti, Fabio; Pietrangelo, Antonello; Clini, Enrico; Girardis, Massimo; Guaraldi, Giovanni; Mussini, Cristina; Cossarizza, Andrea.
Afiliação
  • De Biasi S; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41125, Modena, Italy.
  • Meschiari M; Infectious Diseases Clinics, AOU Policlinico and University of Modena and Reggio Emilia, via del Pozzo 71, 41124, Modena, Italy.
  • Gibellini L; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41125, Modena, Italy.
  • Bellinazzi C; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41125, Modena, Italy.
  • Borella R; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41125, Modena, Italy.
  • Fidanza L; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41125, Modena, Italy.
  • Gozzi L; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41125, Modena, Italy.
  • Iannone A; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41125, Modena, Italy.
  • Lo Tartaro D; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41125, Modena, Italy.
  • Mattioli M; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41125, Modena, Italy.
  • Paolini A; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41125, Modena, Italy.
  • Menozzi M; Infectious Diseases Clinics, AOU Policlinico and University of Modena and Reggio Emilia, via del Pozzo 71, 41124, Modena, Italy.
  • Milic J; Infectious Diseases Clinics, AOU Policlinico and University of Modena and Reggio Emilia, via del Pozzo 71, 41124, Modena, Italy.
  • Franceschi G; Infectious Diseases Clinics, AOU Policlinico and University of Modena and Reggio Emilia, via del Pozzo 71, 41124, Modena, Italy.
  • Fantini R; Respiratory Diseases Unit, AOU Policlinico and University of Modena and Reggio Emilia, via del Pozzo 71, 41124, Modena, Italy.
  • Tonelli R; Respiratory Diseases Unit, AOU Policlinico and University of Modena and Reggio Emilia, via del Pozzo 71, 41124, Modena, Italy.
  • Sita M; Department of Anesthesia and Intensive Care, AOU Policlinico and University of Modena and Reggio Emilia, via del Pozzo 71, 41124, Modena, Italy.
  • Sarti M; Clinical Microbiology Unit, AOU Policlinico, via del Pozzo 71, 41124, Modena, Italy.
  • Trenti T; Clinical Microbiology Unit, AOU Policlinico, via del Pozzo 71, 41124, Modena, Italy.
  • Brugioni L; Emergency Department, MIAC, AOU Policlinico, via del Pozzo 71, 41124, Modena, Italy.
  • Cicchetti L; Labospace, via Apelle 41, 20128, Milano, Italy.
  • Facchinetti F; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41125, Modena, Italy.
  • Pietrangelo A; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41125, Modena, Italy.
  • Clini E; Respiratory Diseases Unit, AOU Policlinico and University of Modena and Reggio Emilia, via del Pozzo 71, 41124, Modena, Italy.
  • Girardis M; Department of Anesthesia and Intensive Care, AOU Policlinico and University of Modena and Reggio Emilia, via del Pozzo 71, 41124, Modena, Italy.
  • Guaraldi G; Infectious Diseases Clinics, AOU Policlinico and University of Modena and Reggio Emilia, via del Pozzo 71, 41124, Modena, Italy.
  • Mussini C; Infectious Diseases Clinics, AOU Policlinico and University of Modena and Reggio Emilia, via del Pozzo 71, 41124, Modena, Italy.
  • Cossarizza A; Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia School of Medicine, Via Campi 287, 41125, Modena, Italy. andrea.cossarizza@unimore.it.
Nat Commun ; 11(1): 3434, 2020 07 06.
Article em En | MEDLINE | ID: mdl-32632085
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Linfócitos T CD4-Positivos / Subpopulações de Linfócitos T / Infecções por Coronavirus / Linfócitos T CD8-Positivos / Betacoronavirus Limite: Aged80 País/Região como assunto: Europa Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Linfócitos T CD4-Positivos / Subpopulações de Linfócitos T / Infecções por Coronavirus / Linfócitos T CD8-Positivos / Betacoronavirus Limite: Aged80 País/Região como assunto: Europa Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Itália