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Kinome capture sequencing of high-grade serous ovarian carcinoma reveals novel mutations in the JAK3 gene.
Mittempergher, Lorenza; Piskorz, Anna M; Bosma, Astrid J; Michaut, Magali; Wisman, G Bea A; Kluin, Roelof J C; Nieuwland, Marja; Brugman, Wim; van der Ven, Kevin J W; Marass, Francesco; Morris, James; Rosenfeld, Nitzan; Jimenez-Linan, Mercedes; de Jong, Steven; van der Zee, Ate G J; Brenton, James D; Bernards, René.
Afiliação
  • Mittempergher L; Division of Molecular Carcinogenesis, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Piskorz AM; Cancer Research UK Cambridge Institute University of Cambridge, Li Ka Shing Centre, Cambridge, United Kingdom.
  • Bosma AJ; Division of Molecular Carcinogenesis, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Michaut M; Division of Molecular Carcinogenesis, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Wisman GBA; Department of Gynecologic Oncology, Cancer Research Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Kluin RJC; Genomics Core Facility, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Nieuwland M; Genomics Core Facility, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Brugman W; Genomics Core Facility, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • van der Ven KJW; Department of Pathology, University Medical Centre Utrecht, Utrecht, The Netherlands.
  • Marass F; Cancer Research UK Cambridge Institute University of Cambridge, Li Ka Shing Centre, Cambridge, United Kingdom.
  • Morris J; Department of Biosystems Science and Engineering and Swiss Institute of Bioinformatics, ETH Zurich, Basel, Switzerland.
  • Rosenfeld N; Cancer Research UK Cambridge Institute University of Cambridge, Li Ka Shing Centre, Cambridge, United Kingdom.
  • Jimenez-Linan M; Cancer Research UK Cambridge Institute University of Cambridge, Li Ka Shing Centre, Cambridge, United Kingdom.
  • de Jong S; Cancer Research UK Major Centre-Cambridge, Cancer Research UK Cambridge Institute, Cambridge, United Kingdom.
  • van der Zee AGJ; Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
  • Brenton JD; Department of Medical Oncology, Cancer Research Center Groningen, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
  • Bernards R; Department of Gynecologic Oncology, Cancer Research Center Groningen, University of Groningen, Groningen, The Netherlands.
PLoS One ; 15(7): e0235766, 2020.
Article em En | MEDLINE | ID: mdl-32639993

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Proteínas Quinases / Proteína Supressora de Tumor p53 / Cistadenocarcinoma Seroso / Proteína BRCA1 / Janus Quinase 3 / Mutação Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Proteínas Quinases / Proteína Supressora de Tumor p53 / Cistadenocarcinoma Seroso / Proteína BRCA1 / Janus Quinase 3 / Mutação Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda