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Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile System.
Simpson, Luke M; Macartney, Thomas J; Nardin, Alice; Fulcher, Luke J; Röth, Sascha; Testa, Andrea; Maniaci, Chiara; Ciulli, Alessio; Ganley, Ian G; Sapkota, Gopal P.
Afiliação
  • Simpson LM; Medical Research Council (MRC) Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
  • Macartney TJ; Medical Research Council (MRC) Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
  • Nardin A; Medical Research Council (MRC) Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
  • Fulcher LJ; Medical Research Council (MRC) Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK; Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
  • Röth S; Medical Research Council (MRC) Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
  • Testa A; Division of Biological Chemistry & Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK; Amphista Therapeutics Ltd, Bo'Ness Road, Newhouse ML1 5UH, UK.
  • Maniaci C; Division of Biological Chemistry & Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK; School of Natural & Environmental Sciences, Chemistry Bedson Building, Kings Road, Newcastle University, Newcastle Upon Tyne NE1 7RU, UK.
  • Ciulli A; Division of Biological Chemistry & Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
  • Ganley IG; Medical Research Council (MRC) Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
  • Sapkota GP; Medical Research Council (MRC) Protein Phosphorylation & Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK. Electronic address: g.sapkota@dundee.ac.uk.
Cell Chem Biol ; 27(9): 1164-1180.e5, 2020 09 17.
Article em En | MEDLINE | ID: mdl-32668203

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Anticorpos de Cadeia Única / Proteólise Limite: Humans Idioma: En Revista: Cell Chem Biol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Anticorpos de Cadeia Única / Proteólise Limite: Humans Idioma: En Revista: Cell Chem Biol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido