[CME: Primary and Secondary Hypercholesterolemia]. / CME: Primäre und sekundäre Hypercholesterinämie.
Praxis (Bern 1994)
; 109(10): 755-762, 2020 Aug.
Article
em De
| MEDLINE
| ID: mdl-32752965
ABSTRACT
CME Primary and Secondary Hypercholesterolemia Abstract. In patients with hypercholesterolemia and an LDL-cholesterol level >5 mmol/l, familial hypercholesterolemia (primary hypercholesterolemia) should be considered. This genetically determined illness should lead to medical therapy and screening for hypercholesterinemia in close relatives. Beside the superelevated LDL-cholesterol levels, additional clinically diagnostic findings and family anamnesis can support the diagnosis of familial hypercholesterolemia. The likelihood of familial hypercholesterolemia can be estimated using the Lipid Clinic Network Score. Additionally, a variety of exogenous factors may have an impact on lipoprotein metabolism and may lead to secondary hypercholesterolemia. Hypothyroidism, cholestasis, nephrotic syndrome or specific medications, among others, should be considered as potential factors leading to high cholesterol levels before familial hypercholesterolemia is suspected or lipid-lowering treatment is started.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Hipercolesterolemia
/
Hiperlipoproteinemia Tipo II
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Limite:
Humans
Idioma:
De
Revista:
Praxis (Bern 1994)
Assunto da revista:
MEDICINA
Ano de publicação:
2020
Tipo de documento:
Article