Apatinib-loaded CalliSpheres Beads for embolization in a rabbit VX2 liver tumor: characterization <i>in vitro</i>, pharmacokinetics and tumor response <i>in vivo</i>.

Shi, Qin; Lu, Yongning; Huang, Songjiang; Zhou, Chen; Yang, Chongtu; Liu, Jiacheng; Ma, Jinqiang; Xiong, Bin

Apatinib-loaded CalliSpheres Beads for embolization in a rabbit VX2 liver tumor: characterization in vitro, pharmacokinetics and tumor response in vivo.

Shi, Qin; Lu, Yongning; Huang, Songjiang; Zhou, Chen; Yang, Chongtu; Liu, Jiacheng; Ma, Jinqiang; Xiong, Bin.

Afiliação

Shi Q; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Lu Y; Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China.
Huang S; Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhou C; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yang C; Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China.
Liu J; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ma J; Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China.
Xiong B; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Drug Deliv ; 27(1): 1301-1307, 2020 Dec.

Article em En | MEDLINE | ID: mdl-32924634

Assuntos

Antineoplásicos/administração & dosagem; Carcinoma Hepatocelular/terapia; Quimioembolização Terapêutica/métodos; Neoplasias Hepáticas/terapia; Microesferas; Piridinas/administração & dosagem; Animais; Antineoplásicos/sangue; Carcinoma Hepatocelular/sangue; Relação Dose-Resposta a Droga; Injeções Intra-Arteriais/métodos; Neoplasias Hepáticas/sangue; Piridinas/sangue; Coelhos; Resultado do Tratamento

Palavras-chave

CalliSpheres beads; Liver cancer; apatinib; pharmacokinetics; transarterial chemoembolization

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Piridinas / Quimioembolização Terapêutica / Carcinoma Hepatocelular / Neoplasias Hepáticas / Microesferas / Antineoplásicos Limite: Animals Idioma: En Revista: Drug Deliv Assunto da revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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