Post-translational Modifications of Fumarase Regulate its Enzyme Activity and Function in Respiration and the DNA Damage Response.

Wang, Suqing; Ramamurthy, Dharanidharan; Tan, Jasper; Liu, Jingyan; Yip, Joyce; Chua, Andrea; Yu, Zhang; Lim, Teck Kwang; Lin, Qingsong; Pines, Ophry; Lehming, Norbert

Wang, Suqing; Ramamurthy, Dharanidharan; Tan, Jasper; Liu, Jingyan; Yip, Joyce; Chua, Andrea; Yu, Zhang; Lim, Teck Kwang; Lin, Qingsong; Pines, Ophry; Lehming, Norbert.

Afiliação

Wang S; Department of Microbiology and Immunology, Cancer Programme at NUSMED, CREATE-NUS-HUJ Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Ramamurthy D; Department of Microbiology and Immunology, Cancer Programme at NUSMED, CREATE-NUS-HUJ Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Tan J; Department of Microbiology and Immunology, Cancer Programme at NUSMED, CREATE-NUS-HUJ Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Liu J; Department of Microbiology and Immunology, Cancer Programme at NUSMED, CREATE-NUS-HUJ Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Yip J; Department of Microbiology and Immunology, Cancer Programme at NUSMED, CREATE-NUS-HUJ Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Chua A; Department of Microbiology and Immunology, Cancer Programme at NUSMED, CREATE-NUS-HUJ Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Yu Z; Department of Microbiology and Immunology, Cancer Programme at NUSMED, CREATE-NUS-HUJ Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Lim TK; Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore.
Lin Q; Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore.
Pines O; Department of Microbiology and Molecular Genetics, IMRIC, Faculty of Medicine, Hebrew University of Jerusalem, Israel; CREATE-NUS-HUJ Programme and Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address: ophryp@ekmd
Lehming N; Department of Microbiology and Immunology, Cancer Programme at NUSMED, CREATE-NUS-HUJ Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; CREATE-NUS-HUJ Programme and Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University

J Mol Biol ; 432(23): 6108-6126, 2020 11 20.

Article em En | MEDLINE | ID: mdl-33058874

Assuntos

Dano ao DNA/genética; Fumarato Hidratase/genética; Processamento de Proteína Pós-Traducional/genética; Respiração/genética; Citoplasma/enzimologia; Citoplasma/genética; Reparo do DNA/genética; Fumarato Hidratase/química; Humanos; Mitocôndrias/enzimologia; Mitocôndrias/genética; Fosforilação/genética; Saccharomyces cerevisiae/genética; Saccharomyces cerevisiae/metabolismo; Ácido Succínico/metabolismo; Ubiquitinação/genética

Palavras-chave

DNA repair; Fumarase; TCA cycle; enzymatic activity; post-translational modification

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Respiração / Dano ao DNA / Processamento de Proteína Pós-Traducional / Fumarato Hidratase Limite: Humans Idioma: En Revista: J Mol Biol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Singapura

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