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Aberrant methylation underlies insulin gene expression in human insulinoma.
Karakose, Esra; Wang, Huan; Inabnet, William; Thakker, Rajesh V; Libutti, Steven; Fernandez-Ranvier, Gustavo; Suh, Hyunsuk; Stevenson, Mark; Kinoshita, Yayoi; Donovan, Michael; Antipin, Yevgeniy; Li, Yan; Liu, Xiaoxiao; Jin, Fulai; Wang, Peng; Uzilov, Andrew; Argmann, Carmen; Schadt, Eric E; Stewart, Andrew F; Scott, Donald K; Lambertini, Luca.
Afiliação
  • Karakose E; From the Diabetes Obesity and Metabolism Institute, The Department of Surgery, The Department of Pathology, The Department of Genetics and Genomics Sciences and The Institute for Genomics and Multiscale Biology, The Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Wang H; Sema4, Stamford, CT, 06902, USA.
  • Inabnet W; From the Diabetes Obesity and Metabolism Institute, The Department of Surgery, The Department of Pathology, The Department of Genetics and Genomics Sciences and The Institute for Genomics and Multiscale Biology, The Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Thakker RV; The Academic Endocrine Unit, University of Oxford, OX3 7LJ, Oxford, UK.
  • Libutti S; The Cancer Institute of New Jersey, New Brunswick, NJ, 08901, USA.
  • Fernandez-Ranvier G; From the Diabetes Obesity and Metabolism Institute, The Department of Surgery, The Department of Pathology, The Department of Genetics and Genomics Sciences and The Institute for Genomics and Multiscale Biology, The Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Suh H; From the Diabetes Obesity and Metabolism Institute, The Department of Surgery, The Department of Pathology, The Department of Genetics and Genomics Sciences and The Institute for Genomics and Multiscale Biology, The Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Stevenson M; The Academic Endocrine Unit, University of Oxford, OX3 7LJ, Oxford, UK.
  • Kinoshita Y; From the Diabetes Obesity and Metabolism Institute, The Department of Surgery, The Department of Pathology, The Department of Genetics and Genomics Sciences and The Institute for Genomics and Multiscale Biology, The Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Donovan M; From the Diabetes Obesity and Metabolism Institute, The Department of Surgery, The Department of Pathology, The Department of Genetics and Genomics Sciences and The Institute for Genomics and Multiscale Biology, The Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Antipin Y; From the Diabetes Obesity and Metabolism Institute, The Department of Surgery, The Department of Pathology, The Department of Genetics and Genomics Sciences and The Institute for Genomics and Multiscale Biology, The Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Li Y; Sema4, Stamford, CT, 06902, USA.
  • Liu X; The Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Jin F; The Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Wang P; The Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, 44106, USA.
  • Uzilov A; From the Diabetes Obesity and Metabolism Institute, The Department of Surgery, The Department of Pathology, The Department of Genetics and Genomics Sciences and The Institute for Genomics and Multiscale Biology, The Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Argmann C; From the Diabetes Obesity and Metabolism Institute, The Department of Surgery, The Department of Pathology, The Department of Genetics and Genomics Sciences and The Institute for Genomics and Multiscale Biology, The Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Schadt EE; Sema4, Stamford, CT, 06902, USA.
  • Stewart AF; From the Diabetes Obesity and Metabolism Institute, The Department of Surgery, The Department of Pathology, The Department of Genetics and Genomics Sciences and The Institute for Genomics and Multiscale Biology, The Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Scott DK; From the Diabetes Obesity and Metabolism Institute, The Department of Surgery, The Department of Pathology, The Department of Genetics and Genomics Sciences and The Institute for Genomics and Multiscale Biology, The Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Lambertini L; Sema4, Stamford, CT, 06902, USA.
Nat Commun ; 11(1): 5210, 2020 10 15.
Article em En | MEDLINE | ID: mdl-33060578
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Regulação Neoplásica da Expressão Gênica / Insulina / Insulinoma Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Regulação Neoplásica da Expressão Gênica / Insulina / Insulinoma Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos