Antagonistic interaction between TTA-A2 and paclitaxel for anti-cancer effects by complex formation with T-type calcium channel.

Kumari, Neema; Dalal, Vikram; Kumar, Pravindra; Rath, Subha Narayan

Kumari, Neema; Dalal, Vikram; Kumar, Pravindra; Rath, Subha Narayan.

Afiliação

Kumari N; Department of Biomedical Engineering, Regenerative Medicine and Stem Cells Laboratory, Indian Institute of Technology Hyderabad, Kandi, Telangana, India.
Dalal V; Department of Biotechnology, Indian Institute of Technology, Hyderabad, Telangana, India.
Kumar P; Department of Biotechnology, Indian Institute of Technology, Roorkee, Uttarakhand, India.
Rath SN; Department of Biotechnology, Indian Institute of Technology, Roorkee, Uttarakhand, India.

J Biomol Struct Dyn ; 40(6): 2395-2406, 2022 04.

Article em En | MEDLINE | ID: mdl-33103598

Assuntos

Benzenoacetamidas; Canais de Cálcio Tipo T; Benzenoacetamidas/uso terapêutico; Canais de Cálcio Tipo T/metabolismo; Linhagem Celular Tumoral; Paclitaxel/farmacologia; Piridinas/uso terapêutico

Palavras-chave

A549; Lung cancer; T-type calcium channel; TTA-A2; paclitaxel; synergistic/antagonistic effect

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Canais de Cálcio Tipo T / Benzenoacetamidas Idioma: En Revista: J Biomol Struct Dyn Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Índia

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