Randomised prospective phase II trial in multiple brain metastases comparing outcomes between hippocampal avoidance whole brain radiotherapy with or without simultaneous integrated boost: HA-SIB-WBRT study protocol.

Chia, Brendan Seng Hup; Leong, Jing Yun; Ong, Ashley Li Kuan; Lim, Cindy; Poon, Shi Hui; Chua, Melvin Lee Kiang; Chua, Kevin Lee Min; Kusumawidjaja, Grace; Chua, Eu Tiong; Wong, Fuh Yong; Lee, Tih Shih

Chia, Brendan Seng Hup; Leong, Jing Yun; Ong, Ashley Li Kuan; Lim, Cindy; Poon, Shi Hui; Chua, Melvin Lee Kiang; Chua, Kevin Lee Min; Kusumawidjaja, Grace; Chua, Eu Tiong; Wong, Fuh Yong; Lee, Tih Shih.

Afiliação

Chia BSH; Division of Radiation Oncology, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore, 169610, Singapore. brendan.chia.s.h@singhealth.com.sg.
Leong JY; Department of Adult Neuro-developmental Service, Institute of Mental Health Singapore, 10 Buangkok View, Singapore, 539747, Singapore.
Ong ALK; Division of Radiation Oncology, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore, 169610, Singapore.
Lim C; Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore, 169610, Singapore.
Poon SH; Department of Psychiatry, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.
Chua MLK; Division of Radiation Oncology, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore, 169610, Singapore.
Chua KLM; Division of Radiation Oncology, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore, 169610, Singapore.
Kusumawidjaja G; Division of Radiation Oncology, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore, 169610, Singapore.
Chua ET; Division of Radiation Oncology, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore, 169610, Singapore.
Wong FY; Division of Radiation Oncology, National Cancer Centre Singapore, 11 Hospital Crescent, Singapore, 169610, Singapore.
Lee TS; Department of Psychiatry, Singapore General Hospital, Outram Road, Singapore, 169608, Singapore.

BMC Cancer ; 20(1): 1045, 2020 Oct 30.

Article em En | MEDLINE | ID: mdl-33126867

Assuntos

Neoplasias Encefálicas/radioterapia; Irradiação Craniana/métodos; Hipocampo/efeitos da radiação; Neoplasias/radioterapia; Tratamentos com Preservação do Órgão/métodos; Qualidade de Vida; Atividades Cotidianas; Adulto; Idoso; Idoso de 80 Anos ou mais; Neoplasias Encefálicas/secundário; Estudos de Casos e Controles; Ensaios Clínicos Fase II como Assunto; Fracionamento da Dose de Radiação; Feminino; Seguimentos; Humanos; Masculino; Pessoa de Meia-Idade; Neoplasias/patologia; Estudos Prospectivos; Ensaios Clínicos Controlados Aleatórios como Assunto; Adulto Jovem

Palavras-chave

Brain metastases; Hippocampal-avoidance whole brain radiotherapy; Study protocol; Whole brain radiotherapy

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Texto completo: 1 Coleções: 01-internacional Temas: Cuidados_paliativos / Geral / Tipos_de_cancer / Outros_tipos / Tratamento / Radioterapia Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Neoplasias Encefálicas / Irradiação Craniana / Tratamentos com Preservação do Órgão / Hipocampo / Neoplasias Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Singapura

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