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Rare case of apatinib acquired resistance induced by point mutation of WRN p.V697F through activation of the PI3K/AKT apoptosis-inhibiting pathway.
Yu, Ruofei; Bai, Hua; Gao, Bingyu; Li, Tangai; He, Xiran; Zhang, Pei; Wang, Jie.
Afiliação
  • Yu R; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Bai H; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Gao B; Emergency Department, Peking University First Hospital, Beijing, China.
  • Li T; Dalian Medical University, Dalian, China.
  • He X; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Zhang P; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Wang J; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Thorac Cancer ; 12(1): 128-132, 2021 01.
Article em En | MEDLINE | ID: mdl-33225619
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Pulmao Base de dados: MEDLINE Assunto principal: Piridinas / Carcinoma Pulmonar de Células não Pequenas / Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas c-akt / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Female / Humans Idioma: En Revista: Thorac Cancer Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Pulmao Base de dados: MEDLINE Assunto principal: Piridinas / Carcinoma Pulmonar de Células não Pequenas / Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas c-akt / Neoplasias Pulmonares / Antineoplásicos Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Female / Humans Idioma: En Revista: Thorac Cancer Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China