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Discovery of novel CA-4 analogs as dual inhibitors of tubulin polymerization and PD-1/PD-L1 interaction for cancer treatment.
Yang, Xuchao; Cheng, Binbin; Xiao, Yao; Xue, Mingming; Liu, Ting; Cao, Hao; Chen, Jianjun.
Afiliação
  • Yang X; School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, 510515, China.
  • Cheng B; School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, 510515, China.
  • Xiao Y; Wuhan Wuchang Hospital, Wuchang Hospital Affiliated to Wuhan University of Science and Technology, 430063, China.
  • Xue M; Tianjin Tiancheng Chemical Co., Ltd., Chemical Street, Binhai New District, Tianjin, 300480, China.
  • Liu T; School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, 510515, China.
  • Cao H; School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, 510515, China.
  • Chen J; School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, 510515, China. Electronic address: jchen21@smu.edu.cn.
Eur J Med Chem ; 213: 113058, 2021 Mar 05.
Article em En | MEDLINE | ID: mdl-33280898
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Estilbenos / Tubulina (Proteína) / Moduladores de Tubulina / Antígeno B7-H1 / Receptor de Morte Celular Programada 1 / Inibidores de Checkpoint Imunológico / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Estilbenos / Tubulina (Proteína) / Moduladores de Tubulina / Antígeno B7-H1 / Receptor de Morte Celular Programada 1 / Inibidores de Checkpoint Imunológico / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China