Association between the histopathological growth patterns of liver metastases and survival after hepatic surgery in breast cancer patients.
NPJ Breast Cancer
; 6(1): 64, 2020 Dec 18.
Article
em En
| MEDLINE
| ID: mdl-33339824
ABSTRACT
Currently, there are no markers to identify patients with liver-only or liver-dominant metastases that would benefit from hepatic surgery. Here we characterized histopathological growth patterns (HGPs) of liver metastases in a consecutive series of 36 breast cancer patients who underwent hepatic surgery. Survival analyses showed that the presence of a desmoplastic HGP in the liver metastases (a rim of fibrous tissue separating cancer cells from the liver parenchyma, present in 20 (56%) patients) is independently associated with favorable progression-free and overall survival when compared with the replacement HGP (cancer cells growing into the liver parenchyma, present in 16 (44%) patients).
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
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Tipos_de_cancer
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Outros_tipos
Base de dados:
MEDLINE
Tipo de estudo:
Risk_factors_studies
Idioma:
En
Revista:
NPJ Breast Cancer
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Bélgica