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Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.
Ryan, Kevin; Bolanos, Ben; Smith, Marissa; Palde, Prakash B; Cuenca, Paulina Delgado; VanArsdale, Todd L; Niessen, Sherry; Zhang, Lianglin; Behenna, Douglas; Ornelas, Martha A; Tran, Khanh T; Kaiser, Stephen; Lum, Lawrence; Stewart, Al; Gajiwala, Ketan S.
Afiliação
  • Ryan K; Structural Biology and Protein Science, Pfizer Worldwide Research and Development, San Diego, California, USA.
  • Bolanos B; Structural Biology and Protein Science, Pfizer Worldwide Research and Development, San Diego, California, USA.
  • Smith M; Oncology Research Unit, Pfizer Worldwide Research and Development, San Diego, California, USA.
  • Palde PB; Oncology Research Unit, Pfizer Worldwide Research and Development, San Diego, California, USA.
  • Cuenca PD; Oncology Research Unit, Pfizer Worldwide Research and Development, San Diego, California, USA.
  • VanArsdale TL; Oncology Research Unit, Pfizer Worldwide Research and Development, San Diego, California, USA.
  • Niessen S; Oncology Research Unit, Pfizer Worldwide Research and Development, San Diego, California, USA.
  • Zhang L; Oncology Research Unit, Pfizer Worldwide Research and Development, San Diego, California, USA.
  • Behenna D; Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, San Diego, California, USA.
  • Ornelas MA; Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, San Diego, California, USA.
  • Tran KT; Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, San Diego, California, USA.
  • Kaiser S; Structural Biology and Protein Science, Pfizer Worldwide Research and Development, San Diego, California, USA.
  • Lum L; Oncology Research Unit, Pfizer Worldwide Research and Development, San Diego, California, USA.
  • Stewart A; Structural Biology and Protein Science, Pfizer Worldwide Research and Development, San Diego, California, USA.
  • Gajiwala KS; Structural Biology and Protein Science, Pfizer Worldwide Research and Development, San Diego, California, USA. Electronic address: ketan.gajiwala@pfizer.com.
J Biol Chem ; 296: 100251, 2021.
Article em En | MEDLINE | ID: mdl-33361107
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Tanquirases / Poli(ADP-Ribose) Polimerase-1 Limite: Female / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Tanquirases / Poli(ADP-Ribose) Polimerase-1 Limite: Female / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos