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Targeting OCT3 attenuates doxorubicin-induced cardiac injury.
Huang, Kevin M; Zavorka Thomas, Megan; Magdy, Tarek; Eisenmann, Eric D; Uddin, Muhammad Erfan; DiGiacomo, Duncan F; Pan, Alexander; Keiser, Markus; Otter, Marcus; Xia, Sherry H; Li, Yang; Jin, Yan; Fu, Qiang; Gibson, Alice A; Bonilla, Ingrid M; Carnes, Cynthia A; Corps, Kara N; Coppola, Vincenzo; Smith, Sakima A; Addison, Daniel; Nies, Anne T; Bundschuh, Ralf; Chen, Taosheng; Lustberg, Maryam B; Wang, Joanne; Oswald, Stefan; Campbell, Moray J; Yan, Pearlly S; Baker, Sharyn D; Hu, Shuiying; Burridge, Paul W; Sparreboom, Alex.
Afiliação
  • Huang KM; Department of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
  • Zavorka Thomas M; Department of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
  • Magdy T; Department of Pharmacology and Center for Pharmacogenomics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
  • Eisenmann ED; Department of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
  • Uddin ME; Department of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
  • DiGiacomo DF; Department of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
  • Pan A; Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH 43210.
  • Keiser M; Department of Pharmacology, University Medicine Greifswald, 17489 Greifswald, Germany.
  • Otter M; Department of Pharmacology, University Medicine Greifswald, 17489 Greifswald, Germany.
  • Xia SH; Department of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
  • Li Y; Department of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
  • Jin Y; Department of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
  • Fu Q; Department of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
  • Gibson AA; Department of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
  • Bonilla IM; Department of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, OH 43210.
  • Carnes CA; Outcomes and Translational Sciences, College of Pharmacy, The Ohio State University, Columbus, OH 43210.
  • Corps KN; Comparative Pathology and Digital Imaging Shared Resource, College of Veterinary Medicine, The Ohio State University, Columbus, OH 43210.
  • Coppola V; Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, Columbus, OH 43210.
  • Smith SA; Division of Cardiovascular Medicine and Department of Internal Medicine, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210.
  • Addison D; Cardio-Oncology Program, Division of Cardiology, The Ohio State University Wexner Medical Center, Columbus, OH 43210.
  • Nies AT; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tübingen, 72074 Stuttgart, Germany.
  • Bundschuh R; iFIT Cluster of Excellence, Image Guided and Functionally Instructed Tumor Therapies, University of Tübingen, 72074 Stuttgart, Germany.
  • Chen T; Department of Physics, College of Arts and Sciences, The Ohio State University, Columbus, OH 43210.
  • Lustberg MB; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105.
  • Wang J; Department of Medical Oncology, College of Medicine and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
  • Oswald S; Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA 98195.
  • Campbell MJ; Department of Pharmacology, University Medicine Greifswald, 17489 Greifswald, Germany.
  • Yan PS; Institute of Pharmacology and Toxicology, Rostock University Medical Center, 18507 Rostock, Germany.
  • Baker SD; Department of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
  • Hu S; Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH 43210.
  • Burridge PW; Department of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
  • Sparreboom A; Department of Pharmaceutics and Pharmacology, College of Pharmacy and Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210.
Proc Natl Acad Sci U S A ; 118(5)2021 02 02.
Article em En | MEDLINE | ID: mdl-33495337
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Doxorrubicina / Transportadores de Ânions Orgânicos Sódio-Independentes / Terapia de Alvo Molecular / Traumatismos Cardíacos Tipo de estudo: Prognostic_studies Limite: Animals / Child / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Doxorrubicina / Transportadores de Ânions Orgânicos Sódio-Independentes / Terapia de Alvo Molecular / Traumatismos Cardíacos Tipo de estudo: Prognostic_studies Limite: Animals / Child / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article