Lung aspergilloma with pituitary invasive aspergillosis presenting as headache and hyponatraemia.
BMJ Case Rep
; 14(1)2021 Jan 27.
Article
em En
| MEDLINE
| ID: mdl-33504528
ABSTRACT
Fungal infections involving the pituitary gland are rare and can be life threatening. A 75-year-old man with hypertension and diabetes mellitus presented with headache and hyponatraemia. Imaging study showed right upper lung mass, and mass resection showed aspergilloma without tissue invasion on histology. The patient developed visual impairment a few weeks later, and MRI of the brain revealed bilateral sphenoid sinusitis and pituitary invasion. The trans-sphenoidal biopsy confirmed invasive Aspergillus infection. His sphenoidal sinuses were endoscopically debrided, and he was treated with oral voriconazole. Pituitary aspergillosis should be considered in the differential diagnosis in patients with lung aspergilloma with headache and sinusitis. Prompt biopsy and antifungal treatment are important due to the high mortality rate of the infection.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Doenças da Hipófise
/
Neuroaspergilose
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Aspergilose Pulmonar
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Síndrome de Secreção Inadequada de HAD
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Idioma:
En
Revista:
BMJ Case Rep
Ano de publicação:
2021
Tipo de documento:
Article