Immune Stimulating Antibody-Photosensitizer Conjugates via Fc-Mediated Dendritic Cell Phagocytosis and Phototriggered Immunogenic Cell Death for KRAS-Mutated Pancreatic Cancer Treatment.

Kim, Dahye; Lee, Sanghee; Na, Kun

Kim, Dahye; Lee, Sanghee; Na, Kun.

Afiliação

Kim D; Department of Biotechnology, Department of Biomedical-Chemical Engineering, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi, 14662, Republic of Korea.
Lee S; Department of Biotechnology, Department of Biomedical-Chemical Engineering, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi, 14662, Republic of Korea.
Na K; Department of Biotechnology, Department of Biomedical-Chemical Engineering, The Catholic University of Korea, 43 Jibong-ro, Wonmi-gu, Bucheon-si, Gyeonggi, 14662, Republic of Korea.

Small ; 17(10): e2006650, 2021 03.

Article em En | MEDLINE | ID: mdl-33590726

Assuntos

Adenocarcinoma; Neoplasias Pancreáticas; Linfócitos T CD8-Positivos; Linhagem Celular Tumoral; Citofagocitose; Humanos; Morte Celular Imunogênica; Neoplasias Pancreáticas/tratamento farmacológico; Fármacos Fotossensibilizantes; Proteínas Proto-Oncogênicas p21(ras)/genética; Distribuição Tecidual

Palavras-chave

antibody-dependent cell phagocytosis; antibody-photosensitizer conjugate; cetuximab; immune complex; immunotherapy; photodynamic therapy

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Adenocarcinoma Limite: Humans Idioma: En Revista: Small Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2021 Tipo de documento: Article

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