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Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages.
Dowling, Jennifer K; Afzal, Remsha; Gearing, Linden J; Cervantes-Silva, Mariana P; Annett, Stephanie; Davis, Gavin M; De Santi, Chiara; Assmann, Nadine; Dettmer, Katja; Gough, Daniel J; Bantug, Glenn R; Hamid, Fidinny I; Nally, Frances K; Duffy, Conor P; Gorman, Aoife L; Liddicoat, Alex M; Lavelle, Ed C; Hess, Christoph; Oefner, Peter J; Finlay, David K; Davey, Gavin P; Robson, Tracy; Curtis, Annie M; Hertzog, Paul J; Williams, Bryan R G; McCoy, Claire E.
Afiliação
  • Dowling JK; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Afzal R; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.
  • Gearing LJ; FutureNeuro, SFI Research Centre, Dublin 2, Ireland.
  • Cervantes-Silva MP; Department of Molecular and Translational Science, Monash University, Clayton, VIC, Australia.
  • Annett S; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Davis GM; Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, VIC, Australia.
  • De Santi C; Department of Molecular and Translational Science, Monash University, Clayton, VIC, Australia.
  • Assmann N; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Dettmer K; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Gough DJ; School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland.
  • Bantug GR; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Hamid FI; School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland.
  • Nally FK; Immunobiology Laboratory, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.
  • Duffy CP; Institute of Functional Genomics, University of Regensburg, Regensburg, Germany.
  • Gorman AL; Department of Molecular and Translational Science, Monash University, Clayton, VIC, Australia.
  • Liddicoat AM; Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC, Australia.
  • Lavelle EC; Immunobiology Laboratory, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.
  • Hess C; Cambridge Institute of Therapeutic Immunology & Infectious Disease, Department of Medicine, University of Cambridge, Cambridge, UK.
  • Oefner PJ; Department of Molecular and Translational Science, Monash University, Clayton, VIC, Australia.
  • Finlay DK; Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC, Australia.
  • Davey GP; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Robson T; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
  • Curtis AM; School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland.
  • Hertzog PJ; School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland.
  • Williams BRG; School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland.
  • McCoy CE; Immunobiology Laboratory, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.
Nat Commun ; 12(1): 1460, 2021 03 05.
Article em En | MEDLINE | ID: mdl-33674584

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Arginase / Interleucina-10 / Macrófagos / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Irlanda

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Arginase / Interleucina-10 / Macrófagos / Mitocôndrias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Irlanda