LncRNA SPOCD1-AS from ovarian cancer extracellular vesicles remodels mesothelial cells to promote peritoneal metastasis via interacting with G3BP1.

Wang, Conghui; Wang, Jiaying; Shen, Xiameng; Li, Mingyue; Yue, Yongfang; Cheng, Xiaodong; Lu, Weiguo; Wang, Xinyu; Xie, Xing

Wang, Conghui; Wang, Jiaying; Shen, Xiameng; Li, Mingyue; Yue, Yongfang; Cheng, Xiaodong; Lu, Weiguo; Wang, Xinyu; Xie, Xing.

Afiliação

Wang C; Women's Reproductive Health Laboratory of Zhejiang Province, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, Zhejiang, China.
Wang J; Women's Reproductive Health Laboratory of Zhejiang Province, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, Zhejiang, China.
Shen X; Women's Reproductive Health Laboratory of Zhejiang Province, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, Zhejiang, China.
Li M; Women's Reproductive Health Laboratory of Zhejiang Province, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, Zhejiang, China.
Yue Y; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, Zhejiang, China.
Cheng X; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, Zhejiang, China.
Lu W; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, Zhejiang, China.
Wang X; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, Zhejiang, China. wangxy@zju.edu.cn.
Xie X; Department of Gynecologic Oncology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, Zhejiang, China. xiex@zju.edu.cn.

J Exp Clin Cancer Res ; 40(1): 101, 2021 Mar 16.

Article em En | MEDLINE | ID: mdl-33726799

Assuntos

Carcinoma Epitelial do Ovário/metabolismo; DNA Helicases/metabolismo; Vesículas Extracelulares/metabolismo; Neoplasias Ovarianas/metabolismo; Neoplasias Peritoneais/secundário; Proteínas de Ligação a Poli-ADP-Ribose/metabolismo; RNA Helicases/metabolismo; Proteínas com Motivo de Reconhecimento de RNA/metabolismo; RNA Longo não Codificante/genética; Animais; Carcinoma Epitelial do Ovário/genética; Carcinoma Epitelial do Ovário/patologia; Linhagem Celular Tumoral; DNA Helicases/genética; Vesículas Extracelulares/patologia; Feminino; Xenoenxertos; Humanos; Camundongos; Camundongos SCID; Metástase Neoplásica; Neoplasias Ovarianas/patologia; Neoplasias Peritoneais/patologia; Proteínas de Ligação a Poli-ADP-Ribose/genética; RNA Helicases/genética; Proteínas com Motivo de Reconhecimento de RNA/genética; RNA Antissenso/genética; RNA Antissenso/metabolismo

Palavras-chave

Extracellular vesicles; G3BP1; Interfering peptides; Mesothelial-to-mesenchymal transition; Ovarian cancer; Peritoneal metastasis; SPOCD1-AS

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias Peritoneais / DNA Helicases / RNA Helicases / RNA Longo não Codificante / Vesículas Extracelulares / Proteínas com Motivo de Reconhecimento de RNA / Proteínas de Ligação a Poli-ADP-Ribose / Carcinoma Epitelial do Ovário Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: J Exp Clin Cancer Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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