Identification of Potent Reverse Indazole Inhibitors for HPK1.

Yu, Elsie C; Methot, Joey L; Fradera, Xavier; Lesburg, Charles A; Lacey, Brian M; Siliphaivanh, Phieng; Liu, Ping; Smith, Dustin M; Xu, Zangwei; Piesvaux, Jennifer A; Kawamura, Shuhei; Xu, Haiyan; Miller, J Richard; Bittinger, Mark; Pasternak, Alexander

Yu, Elsie C; Methot, Joey L; Fradera, Xavier; Lesburg, Charles A; Lacey, Brian M; Siliphaivanh, Phieng; Liu, Ping; Smith, Dustin M; Xu, Zangwei; Piesvaux, Jennifer A; Kawamura, Shuhei; Xu, Haiyan; Miller, J Richard; Bittinger, Mark; Pasternak, Alexander.

Afiliação

Yu EC; Discovery Chemistry, Merck & Co., Inc., Boston, Massachusetts, 02115, United States.
Methot JL; Discovery Chemistry, Merck & Co., Inc., Boston, Massachusetts, 02115, United States.
Fradera X; Computational and Structural Chemistry, Merck & Co., Inc., Boston, Massachusetts, 02115, United States.
Lesburg CA; Computational and Structural Chemistry, Merck & Co., Inc., Boston, Massachusetts, 02115, United States.
Lacey BM; Quantitative Biosciences, Merck & Co., Inc., Boston, Massachusetts, 02115, United States.
Siliphaivanh P; Discovery Chemistry, Merck & Co., Inc., Boston, Massachusetts, 02115, United States.
Liu P; External Discovery Chemistry, Merck & Co Inc., Rahway, New Jersey, 07065, United States.
Smith DM; Pharmacokinetics and Drug Metabolism, Merck & Co., Inc., Boston, Massachusetts, 02115, United States.
Xu Z; Quantitative Biosciences, Merck & Co., Inc., Boston, Massachusetts, 02115, United States.
Piesvaux JA; Quantitative Biosciences, Merck & Co., Inc., Boston, Massachusetts, 02115, United States.
Kawamura S; Discovery Chemistry, Merck & Co., Inc., Boston, Massachusetts, 02115, United States.
Xu H; Quantitative Biosciences, Merck & Co., Inc., Boston, Massachusetts, 02115, United States.
Miller JR; Quantitative Biosciences, Merck & Co., Inc., Boston, Massachusetts, 02115, United States.
Bittinger M; Oncology Early Discovery, Merck & Co., Inc., Boston, Massachusetts, 02115, United States.
Pasternak A; Discovery Chemistry, Merck & Co., Inc., Boston, Massachusetts, 02115, United States.

ACS Med Chem Lett ; 12(3): 459-466, 2021 Mar 11.

Article em En | MEDLINE | ID: mdl-33738073

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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