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Mutated SPOP E3 Ligase Promotes 17ßHSD4 Protein Degradation to Drive Androgenesis and Prostate Cancer Progression.
Shi, Lei; Yan, Yuqian; He, Yundong; Yan, Binyuan; Pan, Yunqian; Orme, Jacob J; Zhang, Jun; Xu, Wanhai; Pang, Jun; Huang, Haojie.
Afiliação
  • Shi L; Department of Radiation Oncology, the Fourth Hospital of Harbin Medical University, Harbin, China.
  • Yan Y; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota.
  • He Y; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota.
  • Yan B; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota.
  • Pan Y; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota.
  • Orme JJ; Department of Urology, Kidney and Urology Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
  • Zhang J; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota.
  • Xu W; Division of Medical Oncology, Department of Internal Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.
  • Pang J; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine and Science, Scottsdale, Arizona.
  • Huang H; Department of Urology, the Fourth Hospital of Harbin Medical University, Harbin, China.
Cancer Res ; 81(13): 3593-3606, 2021 07 01.
Article em En | MEDLINE | ID: mdl-33762355

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Prostata Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Proteínas Repressoras / Proteínas Nucleares / Receptores Androgênicos / Regulação Neoplásica da Expressão Gênica / Proteína Multifuncional do Peroxissomo-2 / Androgênios / Mutação Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Cancer Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Prostata Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Proteínas Repressoras / Proteínas Nucleares / Receptores Androgênicos / Regulação Neoplásica da Expressão Gênica / Proteína Multifuncional do Peroxissomo-2 / Androgênios / Mutação Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Cancer Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China