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Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4'-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity.
Evans, Joanna C; Murugesan, Dinakaran; Post, John M; Mendes, Vitor; Wang, Zhe; Nahiyaan, Navid; Lynch, Sasha L; Thompson, Stephen; Green, Simon R; Ray, Peter C; Hess, Jeannine; Spry, Christina; Coyne, Anthony G; Abell, Chris; Boshoff, Helena I M; Wyatt, Paul G; Rhee, Kyu Y; Blundell, Tom L; Barry, Clifton E; Mizrahi, Valerie.
Afiliação
  • Evans JC; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research & Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, Faculty of Health Sciences, Univer
  • Murugesan D; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, U.K.
  • Post JM; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, U.K.
  • Mendes V; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, U.K.
  • Wang Z; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York 10065, United States.
  • Nahiyaan N; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York 10065, United States.
  • Lynch SL; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research & Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, Faculty of Health Sciences, Univer
  • Thompson S; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, U.K.
  • Green SR; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, U.K.
  • Ray PC; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, U.K.
  • Hess J; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.
  • Spry C; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.
  • Coyne AG; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.
  • Abell C; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.
  • Boshoff HIM; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, United States.
  • Wyatt PG; Drug Discovery Unit, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, U.K.
  • Rhee KY; Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York 10065, United States.
  • Blundell TL; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, U.K.
  • Barry CE; MRC/NHLS/UCT Molecular Mycobacteriology Research Unit & DST/NRF Centre of Excellence for Biomedical TB Research & Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, Faculty of Health Sciences, Univer
  • Mizrahi V; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, United States.
ACS Infect Dis ; 7(6): 1666-1679, 2021 06 11.
Article em En | MEDLINE | ID: mdl-33939919
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Peptídeo Sintases / Mycobacterium tuberculosis Idioma: En Revista: ACS Infect Dis Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Peptídeo Sintases / Mycobacterium tuberculosis Idioma: En Revista: ACS Infect Dis Ano de publicação: 2021 Tipo de documento: Article