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Advances in Tumor Sampling and Sequencing in Breast Cancer and their Application in Precision Diagnostics and Therapeutics.
Lee, Amos Chungwon; Lee, Han-Byoel; Yeom, Huiran; Song, Seo Woo; Kim, Su Deok; Choi, Ahyoun; Lee, Sumin; Lee, Yongju; Han, Wonshik; Kwon, Sunghoon.
Afiliação
  • Lee AC; Interdisciplinary Program in Bioengineering, Seoul National University, Seoul, South Korea.
  • Lee HB; Bio-MAX Institute, Seoul National University, Seoul, South Korea.
  • Yeom H; Department of Surgery, Seoul National University College of Medicine, Seoul, South Korea.
  • Song SW; Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea.
  • Kim SD; Cancer Research Institute, Seoul National University, Seoul, South Korea.
  • Choi A; Department of Electrical and Computer Engineering, Seoul National University, Seoul, South Korea.
  • Lee S; Bio-MAX Institute, Seoul National University, Seoul, South Korea.
  • Lee Y; Department of Electrical and Computer Engineering, Seoul National University, Seoul, South Korea.
  • Han W; Interdisciplinary Program in Bioengineering, Seoul National University, Seoul, South Korea.
  • Kwon S; Department of Electrical and Computer Engineering, Seoul National University, Seoul, South Korea.
Adv Exp Med Biol ; 1187: 215-244, 2021.
Article em En | MEDLINE | ID: mdl-33983581
ABSTRACT
Intra- and Inter-tumoral heterogeneity is one of the main hurdles in diagnosing and treating breast cancer. Selecting, sampling, and sequencing the samples appropriately provide unique opportunities in realizing precision medicine. This chapter reviews some of the past landmarks, state-of-the-art technologies, and future directions of translational research in terms of tumor sampling technologies and sequencing in breast cancer. In the state-of-the-art technologies section, the technologies are categorized in terms of scientific, precision diagnostic, and precision therapeutic tools. Finally, limitations and future directions regarding various translational research for clinical applications using these technologies will be discussed.
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Adv Exp Med Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Coréia do Sul
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias da Mama Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Revista: Adv Exp Med Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Coréia do Sul