GPx-1-encoded adenoviral vector attenuates dopaminergic impairments induced by methamphetamine in GPx-1 knockout mice through modulation of NF-&#954;B transcription factor.

Sharma, Naveen; Shin, Eun-Joo; Pham, Duc Toan; Sharma, Garima; Dang, Duy-Khanh; Duong, Chu Xuan; Kang, Sang Won; Nah, Seung-Yeol; Jang, Choon-Gon; Lei, Xin Gen; Nabeshima, Toshitaka; Bing, Guoying; Jeong, Ji Hoon; Kim, Hyoung-Chun

GPx-1-encoded adenoviral vector attenuates dopaminergic impairments induced by methamphetamine in GPx-1 knockout mice through modulation of NF-κB transcription factor.

Sharma, Naveen; Shin, Eun-Joo; Pham, Duc Toan; Sharma, Garima; Dang, Duy-Khanh; Duong, Chu Xuan; Kang, Sang Won; Nah, Seung-Yeol; Jang, Choon-Gon; Lei, Xin Gen; Nabeshima, Toshitaka; Bing, Guoying; Jeong, Ji Hoon; Kim, Hyoung-Chun.

Afiliação

Sharma N; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, 24341, South Korea; Department of Global Innovative Drugs, Graduate School of Chung-Ang University, College of Medicine, Chung-Ang University, Seoul, 06974, Republic of Korea.
Shin EJ; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, 24341, South Korea.
Pham DT; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, 24341, South Korea.
Sharma G; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, 24341, South Korea.
Dang DK; Pharmacy Faculty, Can Tho University of Medicine and Pharmacy, Can Tho City, 900000, Viet Nam.
Duong CX; Pharmacy Faculty, Can Tho University of Medicine and Pharmacy, Can Tho City, 900000, Viet Nam.
Kang SW; Department of Life Science, College of Natural Science, Ewha Womans University, Seoul, 03760, Republic of Korea.
Nah SY; Ginsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine and Bio/Molecular Informatics Center, Konkuk University, Seoul, 05029, Republic of Korea.
Jang CG; Department of Pharmacology, School of Pharmacy, Sungkyunkwan University, Suwon, 440-746, Republic of Korea.
Lei XG; Department of Animal Science, Cornell University, Ithaca, NY, 14853, USA.
Nabeshima T; Advanced Diagnostic System Research Laboratory, Fujita Health University Graduate School of Health Science, Toyoake, 470-1192, Japan.
Bing G; Anatomy and Neurobiology, University of Kentucky Medical Center, Medical Center MN208 800 Rose Strees, Lexington, KY, 40536, USA.
Jeong JH; Department of Global Innovative Drugs, Graduate School of Chung-Ang University, College of Medicine, Chung-Ang University, Seoul, 06974, Republic of Korea. Electronic address: jhjeong3@cau.ac.kr.
Kim HC; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, 24341, South Korea. Electronic address: kimhc@kangwon.ac.kr.

Food Chem Toxicol ; 154: 112313, 2021 Aug.

Article em En | MEDLINE | ID: mdl-34082047

Assuntos

Dependovirus/genética; Vetores Genéticos; Glutationa Peroxidase/genética; Metanfetamina/toxicidade; NF-kappa B/metabolismo; Animais; Comportamento Animal/efeitos dos fármacos; Dopamina/toxicidade; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Glutationa Peroxidase GPX1

Palavras-chave

GPx-1 gene-encoded adenoviral vector; GPx-1 knockout mice; GPx-1 overexpressing transgenic mice; Methamphetamine-induced dopaminergic toxicity; NF-κB inhibitor; Striatum

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: NF-kappa B / Dependovirus / Vetores Genéticos / Glutationa Peroxidase / Metanfetamina Limite: Animals Idioma: En Revista: Food Chem Toxicol Ano de publicação: 2021 Tipo de documento: Article

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