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Metformin Is a Pyridoxal-5'-phosphate (PLP)-Competitive Inhibitor of SHMT2.
Tramonti, Angela; Cuyàs, Elisabet; Encinar, José Antonio; Pietzke, Matthias; Paone, Alessio; Verdura, Sara; Arbusà, Aina; Martin-Castillo, Begoña; Giardina, Giorgio; Joven, Jorge; Vazquez, Alexei; Contestabile, Roberto; Cutruzzolà, Francesca; Menendez, Javier A.
Afiliação
  • Tramonti A; Institute of Molecular Biology and Pathology, National Research Council, 00185 Rome, Italy.
  • Cuyàs E; Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.
  • Encinar JA; Girona Biomedical Research Institute (IDIBGI), 17190 Girona, Spain.
  • Pietzke M; ProCURE (Program Against Cancer Therapeutic Resistance), Metabolism & Cancer Group, Catalan Institute of Oncology, 17007 Girona, Spain.
  • Paone A; Institute of Research, Development and Innovation in Biotechnology of Elche (IDiBE) and Molecular and Cell Biology Institute (IBMC), Miguel Hernández University (UMH), 03202 Elche, Alicante, Spain.
  • Verdura S; Max Plank Institute for Molecular Genetics, 14195 Berlin, Germany.
  • Arbusà A; Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.
  • Martin-Castillo B; Girona Biomedical Research Institute (IDIBGI), 17190 Girona, Spain.
  • Giardina G; ProCURE (Program Against Cancer Therapeutic Resistance), Metabolism & Cancer Group, Catalan Institute of Oncology, 17007 Girona, Spain.
  • Joven J; Girona Biomedical Research Institute (IDIBGI), 17190 Girona, Spain.
  • Vazquez A; ProCURE (Program Against Cancer Therapeutic Resistance), Metabolism & Cancer Group, Catalan Institute of Oncology, 17007 Girona, Spain.
  • Contestabile R; Girona Biomedical Research Institute (IDIBGI), 17190 Girona, Spain.
  • Cutruzzolà F; Unit of Clinical Research, Catalan Institute of Oncology, 17007 Girona, Girona, Spain.
  • Menendez JA; Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.
Cancers (Basel) ; 13(16)2021 Aug 09.
Article em En | MEDLINE | ID: mdl-34439169
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Idioma: En Revista: Cancers (Basel) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Idioma: En Revista: Cancers (Basel) Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Itália