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On-target IgG hexamerisation driven by a C-terminal IgM tail-piece fusion variant confers augmented complement activation.
Sopp, Joshua M; Peters, Shirley J; Rowley, Tania F; Oldham, Robert J; James, Sonya; Mockridge, Ian; French, Ruth R; Turner, Alison; Beers, Stephen A; Humphreys, David P; Cragg, Mark S.
Afiliação
  • Sopp JM; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Peters SJ; UCB Pharma, Slough, UK.
  • Rowley TF; UCB Pharma, Slough, UK.
  • Oldham RJ; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
  • James S; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Mockridge I; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
  • French RR; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Turner A; UCB Pharma, Slough, UK.
  • Beers SA; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Humphreys DP; UCB Pharma, Slough, UK.
  • Cragg MS; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK. msc@soton.ac.uk.
Commun Biol ; 4(1): 1031, 2021 09 02.
Article em En | MEDLINE | ID: mdl-34475514
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Imunoglobulina M / Ativação do Complemento Limite: Animals / Humans Idioma: En Revista: Commun Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Imunoglobulina M / Ativação do Complemento Limite: Animals / Humans Idioma: En Revista: Commun Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido