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Monolayer platform using human biopsy-derived duodenal organoids for pharmaceutical research.
Yamashita, Tomoki; Inui, Tatsuya; Yokota, Jumpei; Kawakami, Kentaro; Morinaga, Gaku; Takatani, Masahito; Hirayama, Daisuke; Nomoto, Ryuga; Ito, Kohei; Cui, Yunhai; Ruez, Stephanie; Harada, Kazuo; Kishimoto, Wataru; Nakase, Hiroshi; Mizuguchi, Hiroyuki.
Afiliação
  • Yamashita T; Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan.
  • Inui T; Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University Osaka 565-0871, Japan.
  • Yokota J; Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan.
  • Kawakami K; Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan.
  • Morinaga G; Department of Gastroenterology and Hepatology, School of Medicine, Sapporo Medical University, Hokkaido 060-8556, Japan.
  • Takatani M; Department of Medical Oncology, Keiyukai Sapporo Hospital, Hokkaido 003-0027, Japan.
  • Hirayama D; Department of Pharmacokinetics and Nonclinical Safety, Nippon Boehringer Ingelheim Co., Ltd., Hyogo 650-0047, Japan.
  • Nomoto R; Department of Pharmacokinetics and Nonclinical Safety, Nippon Boehringer Ingelheim Co., Ltd., Hyogo 650-0047, Japan.
  • Ito K; Department of Gastroenterology and Hepatology, School of Medicine, Sapporo Medical University, Hokkaido 060-8556, Japan.
  • Cui Y; Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan.
  • Ruez S; Department of Pharmacokinetics and Nonclinical Safety, Nippon Boehringer Ingelheim Co., Ltd., Hyogo 650-0047, Japan.
  • Harada K; Department of Drug Discovery Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, 88400 Biberach, Germany.
  • Kishimoto W; Department of Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim Pharma GmbH & Co. KG, 88400 Biberach, Germany.
  • Nakase H; Laboratory of Applied Environmental Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan.
  • Mizuguchi H; Department of Pharmacokinetics and Nonclinical Safety, Nippon Boehringer Ingelheim Co., Ltd., Hyogo 650-0047, Japan.
Mol Ther Methods Clin Dev ; 22: 263-278, 2021 Sep 10.
Article em En | MEDLINE | ID: mdl-34485610

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Mol Ther Methods Clin Dev Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Mol Ther Methods Clin Dev Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão