Nootkatone protects cartilage against degeneration in mice by inhibiting NF-&#954;B signaling pathway.

Xu, Yue; Zhang, Minfa; Yang, Wanliang; Xia, Bowei; Wang, Wenhan; Pan, Xin

Nootkatone protects cartilage against degeneration in mice by inhibiting NF-κB signaling pathway.

Xu, Yue; Zhang, Minfa; Yang, Wanliang; Xia, Bowei; Wang, Wenhan; Pan, Xin.

Afiliação

Xu Y; Department of Orthopedic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China; Department of Pediatric Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Engineering an
Zhang M; Department of Otolaryngology/Head and Neck Surgery, Institute of Otolaryngology, Affiliated Hospital of Binzhou Medical University, Binzhou, China.
Yang W; Department of Orthopedic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
Xia B; Department of Orthopedic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
Wang W; Department of Orthopedic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China.
Pan X; Department of Orthopedic Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China. Electronic address: xinpanqlyy@126.com.

Int Immunopharmacol ; 100: 108119, 2021 Nov.

Article em En | MEDLINE | ID: mdl-34492535

Assuntos

Cartilagem/efeitos dos fármacos; Cartilagem/metabolismo; Proteínas I-kappa B/metabolismo; Osteoartrite/tratamento farmacológico; Sesquiterpenos Policíclicos/farmacologia; Animais; Células Cultivadas; Condrócitos/efeitos dos fármacos; Condrócitos/metabolismo; Citocinas/metabolismo; Metaloproteinase 13 da Matriz/metabolismo; Camundongos Endogâmicos C57BL; Substâncias Protetoras/farmacologia

Palavras-chave

Cartilage degeneration; IL-1ß induced inflammatory reaction; Nootkatone

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Osteoartrite / Cartilagem / Proteínas I-kappa B / Sesquiterpenos Policíclicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Int Immunopharmacol Assunto da revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article

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