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Novel genomic signature predictive of response to immune checkpoint blockade: A pan-cancer analysis from project Genomics Evidence Neo-plasia Information Exchange (GENIE).
Swami, Nishwant; Hwang, William L; Guo, Jimmy A; Hoffman, Hannah; Abramowitz, Matthew C; Elbakouny, Ziad; Beltran, Himisha; Chipidza, Fallon; Choueiri, Toni; Pra, Alan Dal; Huang, Franklin; Kaochar, Salma; Kantoff, Philip; Kim, Daniel W; Kishan, Amar U; Kobetz, Erin; Marinac, Catherine; Mucci, Lorelei A; Muralidhar, Vinayak; Pollack, Alan; Sanford, Nina N; Schaeffer, Edward M; Spratt, Daniel E; Zhao, Shuang G; Rebbeck, Timothy R; Nguyen, Paul L; Feng, Felix Y; Mahal, Brandon A; Alshalalfa, Mohammed.
Afiliação
  • Swami N; University of Massachusetts Medical School, Worcester, MA, USA.
  • Hwang WL; Massachusetts General Hospital, Boston, MA, USA; Broad Institute, Cambridge MA, USA.
  • Guo JA; Massachusetts General Hospital, Boston, MA, USA; Broad Institute, Cambridge MA, USA; University of California at San Francisco, San Francisco, CA, USA.
  • Hoffman H; Massachusetts General Hospital, Boston, MA, USA.
  • Abramowitz MC; University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center, USA.
  • Elbakouny Z; Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA, USA.
  • Beltran H; Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA, USA.
  • Chipidza F; Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA, USA.
  • Choueiri T; Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA, USA.
  • Pra AD; University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center, USA.
  • Huang F; University of California at San Francisco, San Francisco, CA, USA.
  • Kaochar S; Baylor College of Medicine, Houston, TX, USA.
  • Kantoff P; Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Kim DW; Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA, USA.
  • Kishan AU; University of California Los Angeles, Los Angeles, CA, USA.
  • Kobetz E; University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center, USA.
  • Marinac C; Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA, USA.
  • Mucci LA; Harvard T. H. Chan School of Public Health, Boston, MA, USA.
  • Muralidhar V; Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA, USA.
  • Pollack A; University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center, USA.
  • Sanford NN; University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Schaeffer EM; Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  • Spratt DE; University of Michigan, Ann Arbor, MI, USA.
  • Zhao SG; University of Michigan, Ann Arbor, MI, USA.
  • Rebbeck TR; Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA, USA; Harvard T. H. Chan School of Public Health, Boston, MA, USA.
  • Nguyen PL; Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA, USA.
  • Feng FY; University of California at San Francisco, San Francisco, CA, USA.
  • Mahal BA; University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center, USA. Electronic address: bmahal@med.miami.edu.
  • Alshalalfa M; University of California at San Francisco, San Francisco, CA, USA; Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA, USA. Electronic address: mohamed.alshalalfa@gmail.com.
Cancer Genet ; 258-259: 61-68, 2021 11.
Article em En | MEDLINE | ID: mdl-34551377
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Sequenciamento de Nucleotídeos em Larga Escala / Inibidores de Checkpoint Imunológico / Mutação / Neoplasias Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Cancer Genet Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Biomarcadores Tumorais / Regulação Neoplásica da Expressão Gênica / Sequenciamento de Nucleotídeos em Larga Escala / Inibidores de Checkpoint Imunológico / Mutação / Neoplasias Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Cancer Genet Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos