Advanced hepatocellular carcinoma treated by radiofrequency ablation combined with oncolytic virus and anti-PD-1 antibody therapy: a case report and literature review.
J Int Med Res
; 49(9): 3000605211044596, 2021 Sep.
Article
em En
| MEDLINE
| ID: mdl-34559020
ABSTRACT
The development of an effective therapy for advanced hepatocellular carcinoma (HCC) represents an important global concern. In recent years, the combination of multiple treatment methods with immunotherapy has achieved great progress in patients with advanced HCC. Patient survival has been significantly prolonged, but cases of complete response (CR) remain rare. Here, we report two cases in which CR was achieved by radiofrequency ablation combined with an oncolytic virus (recombinant human adenovirus type 5) and anti-programmed cell death protein 1 antibody. Additionally, a literature review is presented to describe similar advancements in this field and explore viable methods for the treatment of advanced HCC.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
/
Tipos_de_cancer
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Outros_tipos
Base de dados:
MEDLINE
Assunto principal:
Carcinoma Hepatocelular
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Vírus Oncolíticos
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Ablação por Radiofrequência
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Neoplasias Hepáticas
Limite:
Humans
Idioma:
En
Revista:
J Int Med Res
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
China