Surfactant protein C is associated with perineuronal nets and shows age-dependent changes of brain content and hippocampal deposits in wildtype and 3xTg mice.

Schob, Stefan; Puchta, Joana; Winter, Karsten; Michalski, Dominik; Mages, Bianca; Martens, Henrik; Emmer, Alexander; Hoffmann, Karl-Titus; Gaunitz, Frank; Meinicke, Anton; Krause, Matthias; Härtig, Wolfgang

Schob, Stefan; Puchta, Joana; Winter, Karsten; Michalski, Dominik; Mages, Bianca; Martens, Henrik; Emmer, Alexander; Hoffmann, Karl-Titus; Gaunitz, Frank; Meinicke, Anton; Krause, Matthias; Härtig, Wolfgang.

Afiliação

Schob S; Department of Neuroradiology, Clinic and Policlinic of Radiology, University Hospital Halle, Ernst-Grube-Str. 40, 06120 Halle/Saale, Germany. Electronic address: Schob.Stefan@googlemail.com.
Puchta J; Paul Flechsig Institute for Brain Research, University of Leipzig, Liebigstr.19, 04103 Leipzig, Germany; Institute of Neuroradiology, University of Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.
Winter K; Institute for Anatomy, University of Leipzig, Liebigstr. 13, 04103 Leipzig, Germany.
Michalski D; Department of Neurology, University of Leipzig, Liebigstr. 13, 04103 Leipzig, Germany.
Mages B; Institute for Anatomy, University of Leipzig, Liebigstr. 13, 04103 Leipzig, Germany.
Martens H; Synaptic Systems GmbH, Rudolf-Wissell-Str. 28a, 37079 Göttingen, Germany.
Emmer A; Department of Neurology, Martin Luther University Halle-Wittenberg, Ernst-Grube-Str. 40, 06120 Halle/Saale, Germany.
Hoffmann KT; Institute of Neuroradiology, University of Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.
Gaunitz F; Department of Neurosurgery, University of Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.
Meinicke A; Paul Flechsig Institute for Brain Research, University of Leipzig, Liebigstr.19, 04103 Leipzig, Germany; Institute of Neuroradiology, University of Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.
Krause M; Department of Neurosurgery, University of Leipzig, Liebigstr. 20, 04103 Leipzig, Germany.
Härtig W; Paul Flechsig Institute for Brain Research, University of Leipzig, Liebigstr.19, 04103 Leipzig, Germany.

J Chem Neuroanat ; 118: 102036, 2021 12.

Article em En | MEDLINE | ID: mdl-34626771

Assuntos

Química Encefálica/fisiologia; Hipocampo/metabolismo; Rede Nervosa/metabolismo; Proteína C Associada a Surfactante Pulmonar/metabolismo; Envelhecimento/metabolismo; Animais; Astrócitos/metabolismo; Espaço Extracelular/metabolismo; Feminino; Sistema Glinfático/metabolismo; Humanos; Masculino; Camundongos; Camundongos Transgênicos; Rede Nervosa/crescimento & desenvolvimento; Neuroglia/metabolismo; Acoplamento Neurovascular/fisiologia; Proteína Reelina/metabolismo; Subunidade beta da Proteína Ligante de Cálcio S100/metabolismo

Palavras-chave

Extracellular matrix; Hippocampus; Hyperphosphorylated tau; Neurovascular unit; Perineuronal net; Reelin; S100ß; SP-C; VGLUT2; WFA; ß-amyloid

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Química Encefálica / Proteína C Associada a Surfactante Pulmonar / Hipocampo / Rede Nervosa Tipo de estudo: Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: J Chem Neuroanat Assunto da revista: ANATOMIA / NEUROLOGIA / QUIMICA Ano de publicação: 2021 Tipo de documento: Article

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