Malignant Perivascular Epithelioid Cell Tumour in a Savannah Monitor (Varanus exanthematicus).
J Comp Pathol
; 188: 26-31, 2021 Oct.
Article
em En
| MEDLINE
| ID: mdl-34686274
ABSTRACT
A 9-year-old male captive savannah monitor (Varanus exanthematicus) with a history of general debility was submitted for necropsy. Grossly, there were multiple white masses in the colon, mesorchium and tracheal adventitia. Histologically, the lesions were composed of epithelioid to spindloid neoplastic cells arranged in sheets to interlacing and interwoven bundles, and separated by abundant myxoid material or extensive stromal hyalinization and fibrosis with occasional chondroid metaplasia. Perivascular infiltration of epithelioid neoplastic cells was occasionally seen. Neoplastic cells were immunopositive for alpha-smooth muscle actin, melan-A and S100. The unique histological features and concurrent myogenic and melanocytic immunophenotypes suggest a malignant perivascular epithelioid cell tumour. To our knowledge, this is the first report of perivascular epithelioid cell tumours in a non-human species.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
/
Tipos_de_cancer
/
Outros_tipos
Base de dados:
MEDLINE
Assunto principal:
Sarcoma
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Neoplasias de Células Epitelioides Perivasculares
/
Lagartos
Limite:
Animals
Idioma:
En
Revista:
J Comp Pathol
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Taiwan