Chelating Phosphine-N-Heterocyclic Carbene Platinum Complexes via Catalytic Asymmetric Hydrophosphination and Their Cytotoxicity Toward MKN74 and MCF7 Cancer Cell Lines.

Seah, Jeffery Wee Kiong; Lee, Jeannie Xue Ting; Li, Yongxin; Pullarkat, Sumod A; Tan, Nguan Soon; Leung, Pak-Hing

Seah, Jeffery Wee Kiong; Lee, Jeannie Xue Ting; Li, Yongxin; Pullarkat, Sumod A; Tan, Nguan Soon; Leung, Pak-Hing.

Afiliação

Seah JWK; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
Lee JXT; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, 11 Mandalay Road, Singapore 308232, Singapore.
Li Y; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
Pullarkat SA; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
Tan NS; Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, 11 Mandalay Road, Singapore 308232, Singapore.
Leung PH; School of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore.

Inorg Chem ; 60(22): 17276-17287, 2021 Nov 15.

Article em En | MEDLINE | ID: mdl-34709031

Assuntos

Antineoplásicos/farmacologia; Quelantes/farmacologia; Metano/análogos & derivados; Compostos Organoplatínicos/farmacologia; Fosfinas/farmacologia; Antineoplásicos/síntese química; Antineoplásicos/química; Quelantes/síntese química; Quelantes/química; Relação Dose-Resposta a Droga; Ensaios de Seleção de Medicamentos Antitumorais; Humanos; Metano/química; Metano/farmacologia; Estrutura Molecular; Compostos Organoplatínicos/química; Fosfinas/química; Células Tumorais Cultivadas

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Compostos Organoplatínicos / Fosfinas / Quelantes / Metano / Antineoplásicos Limite: Humans Idioma: En Revista: Inorg Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Singapura

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google