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Digitoxin promotes apoptosis and inhibits proliferation and migration by reducing HIF-1α and STAT3 in KRAS mutant human colon cancer cells.
Mi, Chunliu; Cao, Xiangxiang; Ma, Kai; Wei, Mian; Xu, Wenjing; Lin, Yan; Zhang, Jihong; Wang, Tian-Yun.
Afiliação
  • Mi C; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, School of Basic Medicine, Xinxiang Medical University, Xinxiang, 453003, Henan, China.
  • Cao X; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, School of Basic Medicine, Xinxiang Medical University, Xinxiang, 453003, Henan, China; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Xinxiang Medical University, X
  • Ma K; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, School of Basic Medicine, Xinxiang Medical University, Xinxiang, 453003, Henan, China; School of Pharmacy, Xinxiang Medical University, Xinxiang, 453003, Henan, China.
  • Wei M; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, School of Basic Medicine, Xinxiang Medical University, Xinxiang, 453003, Henan, China; School of Life Sciences and Technology, Xinxiang Medical University, Xinxiang, 453003, Henan, China.
  • Xu W; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, School of Basic Medicine, Xinxiang Medical University, Xinxiang, 453003, Henan, China; School of Pharmacy, Xinxiang Medical University, Xinxiang, 453003, Henan, China.
  • Lin Y; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, School of Basic Medicine, Xinxiang Medical University, Xinxiang, 453003, Henan, China; School of Nursing, Xinxiang Medical University, Xinxiang, 453003, Henan, China.
  • Zhang J; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, School of Basic Medicine, Xinxiang Medical University, Xinxiang, 453003, Henan, China.
  • Wang TY; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, School of Basic Medicine, Xinxiang Medical University, Xinxiang, 453003, Henan, China; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Xinxiang Medical University, X
Chem Biol Interact ; 351: 109729, 2022 Jan 05.
Article em En | MEDLINE | ID: mdl-34717917
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Colon_e_reto Base de dados: MEDLINE Assunto principal: Movimento Celular / Apoptose / Proliferação de Células / Digitoxina / Neoplasias / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Chem Biol Interact Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Colon_e_reto Base de dados: MEDLINE Assunto principal: Movimento Celular / Apoptose / Proliferação de Células / Digitoxina / Neoplasias / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Chem Biol Interact Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China