Loss of Profilin3 Impairs Spermiogenesis by Affecting Acrosome Biogenesis, Autophagy, Manchette Development and Mitochondrial Organization.

Umer, Naila; Arévalo, Lena; Phadke, Sharang; Lohanadan, Keerthika; Kirfel, Gregor; Sons, Dominik; Sofia, Denise; Witke, Walter; Schorle, Hubert

Umer, Naila; Arévalo, Lena; Phadke, Sharang; Lohanadan, Keerthika; Kirfel, Gregor; Sons, Dominik; Sofia, Denise; Witke, Walter; Schorle, Hubert.

Afiliação

Umer N; Department of Developmental Pathology, Institute of Pathology, University Hospital Bonn, Bonn, Germany.
Arévalo L; Department of Developmental Pathology, Institute of Pathology, University Hospital Bonn, Bonn, Germany.
Phadke S; Department of Developmental Pathology, Institute of Pathology, University Hospital Bonn, Bonn, Germany.
Lohanadan K; Institute for Cell Biology, University of Bonn, Bonn, Germany.
Kirfel G; Institute for Cell Biology, University of Bonn, Bonn, Germany.
Sons D; Department of Membrane Biochemistry, Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.
Sofia D; Institute of Genetics, University of Bonn, Bonn, Germany.
Witke W; Institute of Genetics, University of Bonn, Bonn, Germany.
Schorle H; Department of Developmental Pathology, Institute of Pathology, University Hospital Bonn, Bonn, Germany.

Front Cell Dev Biol ; 9: 749559, 2021.

Article em En | MEDLINE | ID: mdl-34869336

Palavras-chave

acrosome biogenesis; autophagy; globozoospermia; male fertility; profilin 3; sperm biology

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Idioma: En Revista: Front Cell Dev Biol Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha

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