Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) agonists in islet transplantation: Endogenous in vivo regulatory T cell expansion promotes prolonged allograft survival.

Marfil-Garza, Braulio A; Pawlick, Rena L; Szeto, Jake; Kroger, Charles; Tahiliani, Vikas; Hefler, Joshua; Dadheech, Nidheesh; Seavey, Mathew M; Wolf, Jeffrey; Jasuja, Rahul R; James Shapiro, A M

Marfil-Garza, Braulio A; Pawlick, Rena L; Szeto, Jake; Kroger, Charles; Tahiliani, Vikas; Hefler, Joshua; Dadheech, Nidheesh; Seavey, Mathew M; Wolf, Jeffrey; Jasuja, Rahul R; James Shapiro, A M.

Afiliação

Marfil-Garza BA; Department of Surgery, University of Alberta, Edmonton, Canada.
Pawlick RL; National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico City, Mexico.
Szeto J; CHRISTUS-LatAm Hub - Excellence and Innovation Center, Monterrey, Mexico.
Kroger C; Department of Surgery, University of Alberta, Edmonton, Canada.
Tahiliani V; Department of Surgery, University of Alberta, Edmonton, Canada.
Hefler J; Heat Biologics, Inc./Pelican Therapeutics, Inc., Morrisville, North Carolina.
Dadheech N; Heat Biologics, Inc./Pelican Therapeutics, Inc., Morrisville, North Carolina.
Seavey MM; Department of Surgery, University of Alberta, Edmonton, Canada.
Wolf J; Department of Surgery, University of Alberta, Edmonton, Canada.
Jasuja RR; Heat Biologics, Inc./Pelican Therapeutics, Inc., Morrisville, North Carolina.
James Shapiro AM; Heat Biologics, Inc./Pelican Therapeutics, Inc., Morrisville, North Carolina.

Am J Transplant ; 22(4): 1101-1114, 2022 04.

Article em En | MEDLINE | ID: mdl-34965021

Assuntos

Transplante das Ilhotas Pancreáticas; Aloenxertos; Animais; Rejeição de Enxerto/etiologia; Sobrevivência de Enxerto; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Endogâmicos C57BL; Camundongos Endogâmicos CBA; Linfócitos T Reguladores

Palavras-chave

T cell mediated (TCMR); basic (laboratory) research / science; costimulation molecule specific; endocrinology / diabetology; experimental; immune regulation; immunosuppressant - fusion proteins and monoclonal antibodies; immunosuppression / immune modulation; islet transplantation; rejection; tolerance; translational research / science

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Transplante das Ilhotas Pancreáticas Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Am J Transplant Assunto da revista: TRANSPLANTE Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá

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