The P5-type ATPase ATP13A1 modulates major histocompatibility complex I-related protein 1 (MR1)-mediated antigen presentation.

Kulicke, Corinna A; De Zan, Erica; Hein, Zeynep; Gonzalez-Lopez, Claudia; Ghanwat, Swapnil; Veerapen, Natacha; Besra, Gurdyal S; Klenerman, Paul; Christianson, John C; Springer, Sebastian; Nijman, Sebastian M; Cerundolo, Vincenzo; Salio, Mariolina

Kulicke, Corinna A; De Zan, Erica; Hein, Zeynep; Gonzalez-Lopez, Claudia; Ghanwat, Swapnil; Veerapen, Natacha; Besra, Gurdyal S; Klenerman, Paul; Christianson, John C; Springer, Sebastian; Nijman, Sebastian M; Cerundolo, Vincenzo; Salio, Mariolina.

Afiliação

Kulicke CA; MRC Human Immunology Unit, Radcliffe Department of Medicine, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom. Electronic address: kulicke@ohsu.edu.
De Zan E; Nuffield Department of Medicine, Ludwig Institute for Cancer Research Ltd and Target Discovery Institute, University of Oxford, Oxford, United Kingdom.
Hein Z; Department of Life Sciences and Chemistry, Jacobs University, Bremen, Germany.
Gonzalez-Lopez C; MRC Human Immunology Unit, Radcliffe Department of Medicine, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Ghanwat S; Department of Life Sciences and Chemistry, Jacobs University, Bremen, Germany.
Veerapen N; School of Biosciences, University of Birmingham, Birmingham, United Kingdom.
Besra GS; School of Biosciences, University of Birmingham, Birmingham, United Kingdom.
Klenerman P; Peter Medawar Building, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Christianson JC; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, United Kingdom.
Springer S; Department of Life Sciences and Chemistry, Jacobs University, Bremen, Germany.
Nijman SM; Nuffield Department of Medicine, Ludwig Institute for Cancer Research Ltd and Target Discovery Institute, University of Oxford, Oxford, United Kingdom.
Cerundolo V; MRC Human Immunology Unit, Radcliffe Department of Medicine, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.
Salio M; MRC Human Immunology Unit, Radcliffe Department of Medicine, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom. Electronic address: mariolina.salio@imm.ox.ac.uk.

J Biol Chem ; 298(2): 101542, 2022 02.

Article em En | MEDLINE | ID: mdl-34968463

Assuntos

Apresentação de Antígeno; Antígenos de Histocompatibilidade Classe I; Complexo Principal de Histocompatibilidade; Antígenos de Histocompatibilidade Menor; ATPases do Tipo-P; Antígenos de Histocompatibilidade Classe I/metabolismo; Humanos; Complexo Principal de Histocompatibilidade/imunologia; Antígenos de Histocompatibilidade Menor/imunologia; ATPases do Tipo-P/imunologia

Palavras-chave

ATP13A1; HAP1; MHC I-related protein 1 (MR1); MR1-restricted T cell (MR1T); P5-type ATPase; antigen presentation; gene trap; mucosal-associated invariant T cell (MAIT); protein trafficking

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Antígenos de Histocompatibilidade Classe I / Antígenos de Histocompatibilidade Menor / Apresentação de Antígeno / ATPases do Tipo-P / Complexo Principal de Histocompatibilidade Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2022 Tipo de documento: Article

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