Change in plasma &#945;-tocopherol associations with attenuated pulmonary function decline and with CYP4F2 missense variation.

Xu, Jiayi; Guertin, Kristin A; Gaddis, Nathan C; Agler, Anne H; Parker, Robert S; Feldman, Jared M; Kristal, Alan R; Arnold, Kathryn B; Goodman, Phyllis J; Tangen, Catherine M; Hancock, Dana B; Cassano, Patricia A

Change in plasma α-tocopherol associations with attenuated pulmonary function decline and with CYP4F2 missense variation.

Xu, Jiayi; Guertin, Kristin A; Gaddis, Nathan C; Agler, Anne H; Parker, Robert S; Feldman, Jared M; Kristal, Alan R; Arnold, Kathryn B; Goodman, Phyllis J; Tangen, Catherine M; Hancock, Dana B; Cassano, Patricia A.

Afiliação

Xu J; Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
Guertin KA; Pamela Sklar Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Gaddis NC; Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
Agler AH; Department of Public Health Sciences, University of Connecticut School of Medicine, Farmington, CT, USA.
Parker RS; GenOmics, Bioinformatics, and Translational Research Center, Biostatistics and Epidemiology Division, RTI International, Research Triangle Park, NC, USA.
Feldman JM; Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
Kristal AR; Abbott, Columbus, OH, USA.
Arnold KB; Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
Goodman PJ; Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
Tangen CM; Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Hancock DB; Department of Epidemiology, University of Washington, Seattle, WA, USA.
Cassano PA; SWOG Statistics and Data Management Center, Seattle, WA, USA.

Am J Clin Nutr ; 115(4): 1205-1216, 2022 04 01.

Article em En | MEDLINE | ID: mdl-35040869

Assuntos

Pulmão; alfa-Tocoferol; Família 4 do Citocromo P450; Volume Expiratório Forçado; Humanos; Masculino; Espirometria; Vitamina E

Palavras-chave

CYP4F2; clinical trial; continental population groups; genome-wide association study; human; male; pulmonary function tests; smoking; vitamin E

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Alfa-Tocoferol / Pulmão Tipo de estudo: Clinical_trials / Prognostic_studies / Risk_factors_studies Limite: Humans / Male Idioma: En Revista: Am J Clin Nutr Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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