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PI3Kδ/γ inhibition promotes human CART cell epigenetic and metabolic reprogramming to enhance antitumor cytotoxicity.
Funk, Christopher Ronald; Wang, Shuhua; Chen, Kevin Z; Waller, Alexandra; Sharma, Aditi; Edgar, Claudia L; Gupta, Vikas A; Chandrakasan, Shanmuganathan; Zoine, Jaquelyn T; Fedanov, Andrew; Raikar, Sunil S; Koff, Jean L; Flowers, Christopher R; Coma, Silvia; Pachter, Jonathan A; Ravindranathan, Sruthi; Spencer, H Trent; Shanmugam, Mala; Waller, Edmund K.
Afiliação
  • Funk CR; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.
  • Wang S; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.
  • Chen KZ; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.
  • Waller A; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.
  • Sharma A; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.
  • Edgar CL; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.
  • Gupta VA; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.
  • Chandrakasan S; Division of Bone Marrow Transplant and.
  • Zoine JT; Cell and Gene Therapy Program, Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, GA.
  • Fedanov A; Cell and Gene Therapy Program, Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, GA.
  • Raikar SS; Cell and Gene Therapy Program, Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, GA.
  • Koff JL; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.
  • Flowers CR; Cell and Gene Therapy Program, Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, GA.
  • Coma S; Department of Lymphoma/Myeloma, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, TX; and.
  • Pachter JA; Verastem Oncology Inc, Needham, MA.
  • Ravindranathan S; Verastem Oncology Inc, Needham, MA.
  • Spencer HT; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.
  • Shanmugam M; Cell and Gene Therapy Program, Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, GA.
  • Waller EK; Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA.
Blood ; 139(4): 523-537, 2022 01 27.
Article em En | MEDLINE | ID: mdl-35084470
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Purinas / Leucemia Linfocítica Crônica de Células B / Imunoterapia Adotiva / Inibidores de Fosfoinositídeo-3 Quinase / Isoquinolinas Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Gabão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Purinas / Leucemia Linfocítica Crônica de Células B / Imunoterapia Adotiva / Inibidores de Fosfoinositídeo-3 Quinase / Isoquinolinas Limite: Animals / Humans Idioma: En Revista: Blood Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Gabão