Oncolytic vaccinia virus injected intravenously sensitizes pancreatic neuroendocrine tumors and metastases to immune checkpoint blockade.

Inoue, Mitsuko; Kim, Minah; Inoue, Tomoyoshi; Tait, Madeline; Byrne, Thomas; Nitschké, Maximilian; Murer, Patrizia; Cha, Howard; Subramanian, Aishwarya; De Silva, Naomi; Chiaverotti, Teresa; McDonald, Donald M

Inoue, Mitsuko; Kim, Minah; Inoue, Tomoyoshi; Tait, Madeline; Byrne, Thomas; Nitschké, Maximilian; Murer, Patrizia; Cha, Howard; Subramanian, Aishwarya; De Silva, Naomi; Chiaverotti, Teresa; McDonald, Donald M.

Afiliação

Inoue M; UCSF Helen Diller Family Comprehensive Cancer Center, Cardiovascular Research Institute and Department of Anatomy, University of California, San Francisco, 513 Parnassus Avenue, Room S1349, San Francisco, CA 94143-0452, USA.
Kim M; UCSF Helen Diller Family Comprehensive Cancer Center, Cardiovascular Research Institute and Department of Anatomy, University of California, San Francisco, 513 Parnassus Avenue, Room S1349, San Francisco, CA 94143-0452, USA.
Inoue T; UCSF Helen Diller Family Comprehensive Cancer Center, Cardiovascular Research Institute and Department of Anatomy, University of California, San Francisco, 513 Parnassus Avenue, Room S1349, San Francisco, CA 94143-0452, USA.
Tait M; UCSF Helen Diller Family Comprehensive Cancer Center, Cardiovascular Research Institute and Department of Anatomy, University of California, San Francisco, 513 Parnassus Avenue, Room S1349, San Francisco, CA 94143-0452, USA.
Byrne T; UCSF Helen Diller Family Comprehensive Cancer Center, Cardiovascular Research Institute and Department of Anatomy, University of California, San Francisco, 513 Parnassus Avenue, Room S1349, San Francisco, CA 94143-0452, USA.
Nitschké M; UCSF Helen Diller Family Comprehensive Cancer Center, Cardiovascular Research Institute and Department of Anatomy, University of California, San Francisco, 513 Parnassus Avenue, Room S1349, San Francisco, CA 94143-0452, USA.
Murer P; UCSF Helen Diller Family Comprehensive Cancer Center, Cardiovascular Research Institute and Department of Anatomy, University of California, San Francisco, 513 Parnassus Avenue, Room S1349, San Francisco, CA 94143-0452, USA.
Cha H; UCSF Helen Diller Family Comprehensive Cancer Center, Cardiovascular Research Institute and Department of Anatomy, University of California, San Francisco, 513 Parnassus Avenue, Room S1349, San Francisco, CA 94143-0452, USA.
Subramanian A; UCSF Helen Diller Family Comprehensive Cancer Center, Cardiovascular Research Institute and Department of Anatomy, University of California, San Francisco, 513 Parnassus Avenue, Room S1349, San Francisco, CA 94143-0452, USA.
De Silva N; SillaJen Biotherapeutics Inc., San Francisco, CA 94111, USA.
Chiaverotti T; SillaJen Biotherapeutics Inc., San Francisco, CA 94111, USA.
McDonald DM; UCSF Helen Diller Family Comprehensive Cancer Center, Cardiovascular Research Institute and Department of Anatomy, University of California, San Francisco, 513 Parnassus Avenue, Room S1349, San Francisco, CA 94143-0452, USA.

Mol Ther Oncolytics ; 24: 299-318, 2022 Mar 17.

Article em En | MEDLINE | ID: mdl-35118189

Palavras-chave

A/J mice; NK cells; PD-1; Pexa-Vec; RIP1-Tag2 mice; apoptosis; cytotoxic T cells; hypoglycemia; insulin; liver metastasis; regression

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Mol Ther Oncolytics Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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