miR-7/TGF-ß2 axis sustains acidic tumor microenvironment-induced lung cancer metastasis.
Acta Pharm Sin B
; 12(2): 821-837, 2022 Feb.
Article
em En
| MEDLINE
| ID: mdl-35251919
AOM/DSS, azoxymethane/dextran sodium sulfate; Acidic tumor microenvironment; B[a]P, benzopyrene; CA9, carbonic anhydrase IX; DAB, diaminobenzidine; DAVID, Database for Annotation, Visualization, and Integrated Discovery; DEGs, differentially expressed genes; DEN, diethylnitrosamine; DEPs, differentially expressed proteins; DSS, dextran sodium sulfate; GEMMs, genetically engineered tumor mouse models; GSEA, gene set enrichment analysis; IHC, immunohistochemistry; ISH, in situ hybridization; Invasion; KEGG, Kyoto Encyclopedia of Genes and Genomes; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; Lung cancer; MCT, monocarboxylate transporter; Metastasis; NHE, Na+/H+ exchanger; NSCLC, non-small cell lung cancer; PCR, polymerase chain reaction; TGF-ß2; TME, tumor microenvironment; TMT, tandem mass tagging; V-ATPase, vacuolar ATPase; miR-7-5p; pH
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
/
Tipos_de_cancer
/
Pulmao
Base de dados:
MEDLINE
Idioma:
En
Revista:
Acta Pharm Sin B
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
China