Lingguizhugan decoction protects PC12 cells against Aß<sub>25-35</sub>-induced oxidative stress and neuroinflammation by modulating NF-&#954;B/MAPK signaling pathways.

Han, Jing; Zhang, Haotian; Zhang, Yu; Zhang, Zan; Yu, Maomao; Wang, Sijie; Han, Fei

Lingguizhugan decoction protects PC12 cells against Aß_25-35-induced oxidative stress and neuroinflammation by modulating NF-κB/MAPK signaling pathways.

Han, Jing; Zhang, Haotian; Zhang, Yu; Zhang, Zan; Yu, Maomao; Wang, Sijie; Han, Fei.

Afiliação

Han J; School of Pharmacy, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenhe District, Shenyang, 110016, China. Electronic address: hhanjing1023@163.com.
Zhang H; School of Pharmacy, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenhe District, Shenyang, 110016, China. Electronic address: 291260325@qq.com.
Zhang Y; School of Pharmacy, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenhe District, Shenyang, 110016, China. Electronic address: 773874506@qq.com.
Zhang Z; School of Pharmacy, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenhe District, Shenyang, 110016, China. Electronic address: 1454116917@qq.com.
Yu M; School of Pharmacy, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenhe District, Shenyang, 110016, China. Electronic address: 960728459@qq.com.
Wang S; School of Pharmacy, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenhe District, Shenyang, 110016, China. Electronic address: 1695890091@qq.com.
Han F; School of Pharmacy, Shenyang Pharmaceutical University, No.103 Wenhua Road, Shenhe District, Shenyang, 110016, China. Electronic address: hanfei_spu@163.com.

J Ethnopharmacol ; 292: 115194, 2022 Jun 28.

Article em En | MEDLINE | ID: mdl-35304276

Assuntos

Doença de Alzheimer; NF-kappa B; Peptídeos beta-Amiloides/metabolismo; Peptídeos beta-Amiloides/toxicidade; Animais; Apoptose; Glicogênio Sintase Quinase 3 beta/metabolismo; Sistema de Sinalização das MAP Quinases; Inibidor de NF-kappaB alfa/metabolismo; NF-kappa B/metabolismo; Doenças Neuroinflamatórias; Estresse Oxidativo; Células PC12; Ratos

Palavras-chave

Alzheimer's disease; Amyloid beta peptide; Lingguizhugan decoction; Nuclear factor-κB/mitogen-activated protein kinase (NF-κB/MAPK) signaling pathways; Tau hyperphosphorylation

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: NF-kappa B / Doença de Alzheimer Limite: Animals Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2022 Tipo de documento: Article

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