Pharmacological Modulation of Apoptosis and Autophagy in Pancreatic Cancer Treatment.

Selvarajoo, Nityaa; Stanslas, Johnson; Islam, Mohammad Kaisarul; Sagineedu, Sreenivasa Rao; Lian, Ho Kok; Lim, Jonathan Chee Woei

Selvarajoo, Nityaa; Stanslas, Johnson; Islam, Mohammad Kaisarul; Sagineedu, Sreenivasa Rao; Lian, Ho Kok; Lim, Jonathan Chee Woei.

Afiliação

Selvarajoo N; Pharmacotherapeutics Unit, Department of Medicine, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.
Stanslas J; Pharmacotherapeutics Unit, Department of Medicine, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.
Islam MK; Pharmacotherapeutics Unit, Department of Medicine, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.
Sagineedu SR; Department of Pharmaceutical Chemistry, School of Pharmacy, International Medical University, 57000 Kuala Lumpur, Malaysia.
Lian HK; Department of Pathology, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.
Lim JCW; Pharmacotherapeutics Unit, Department of Medicine, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.

Mini Rev Med Chem ; 22(20): 2581-2595, 2022.

Article em En | MEDLINE | ID: mdl-35331093

Assuntos

Antineoplásicos; Metformina; Neoplasias Pancreáticas; Antineoplásicos/farmacologia; Antineoplásicos/uso terapêutico; Apoptose; Autofagia; Linhagem Celular Tumoral; Proliferação de Células; Cloroquina/farmacologia; Receptores ErbB; Fluoruracila/uso terapêutico; Humanos; Metformina/uso terapêutico; Neoplasias Pancreáticas/tratamento farmacológico; Neoplasias Pancreáticas/patologia; Fosfatidilinositol 3-Quinases/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Resveratrol/farmacologia; Sirolimo/farmacologia; Sirolimo/uso terapêutico; Serina-Treonina Quinases TOR/metabolismo; Neoplasias Pancreáticas

Palavras-chave

Pancreatic cancer; apoptosis; autophagy; autophagy modulators; cancer drugs; chemoresistance

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Metformina / Antineoplásicos Tipo de estudo: Prognostic_studies / Systematic_reviews Limite: Humans Idioma: En Revista: Mini Rev Med Chem Assunto da revista: QUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Malásia

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