Kidney-Derived Methylated PAX2 Sequences in the Urine of Healthy Subjects as a Convenient Model for Optimizing Methylation-Based Liquid biopsy.

Zhou, Xiang-Cheng; Chen, Qiu-Ping; Yuan, Jia-Jia; Zhou, Shuai; Li, Mi; Zhou, Wei-Ping; Qin, Yan; Deng, Hua; Zhang, Liang

Zhou, Xiang-Cheng; Chen, Qiu-Ping; Yuan, Jia-Jia; Zhou, Shuai; Li, Mi; Zhou, Wei-Ping; Qin, Yan; Deng, Hua; Zhang, Liang.

Afiliação

Zhou XC; Maternal and Child Health Research Institute, Translational Medicine Center, Guangdong Women and Children Hospital, Guangzhou, 511400, China.
Chen QP; Maternal and Child Health Research Institute, Translational Medicine Center, Guangdong Women and Children Hospital, Guangzhou, 511400, China.
Yuan JJ; Maternal and Child Health Research Institute, Translational Medicine Center, Guangdong Women and Children Hospital, Guangzhou, 511400, China.
Zhou S; Maternal and Child Health Research Institute, Translational Medicine Center, Guangdong Women and Children Hospital, Guangzhou, 511400, China.
Li M; Maternal and Child Health Research Institute, Translational Medicine Center, Guangdong Women and Children Hospital, Guangzhou, 511400, China.
Zhou WP; Maternal and Child Health Research Institute, Translational Medicine Center, Guangdong Women and Children Hospital, Guangzhou, 511400, China.
Qin Y; Department of Pathology, Guangdong Women and Children Hospital, Guangzhou, 511400, China.
Deng H; Maternal and Child Health Research Institute, Translational Medicine Center, Guangdong Women and Children Hospital, Guangzhou, 511400, China. dhdoggy@163.com.
Zhang L; Maternal and Child Health Research Institute, Translational Medicine Center, Guangdong Women and Children Hospital, Guangzhou, 511400, China. zhangliang1999@tsinghua.org.cn.

Mol Biotechnol ; 64(10): 1088-1094, 2022 Oct.

Article em En | MEDLINE | ID: mdl-35412261

Assuntos

Ácidos Nucleicos Livres; Metilação de DNA; Ácidos Nucleicos Livres/genética; DNA/análise; Voluntários Saudáveis; Humanos; Rim/química; Biópsia Líquida; Fator de Transcrição PAX2/genética

Palavras-chave

Bisulfite conversion; Cell-free DNA; Methylation detection; Urine handling conditions; qMS-PCR

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Metilação de DNA / Ácidos Nucleicos Livres Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Biotechnol Assunto da revista: BIOLOGIA MOLECULAR / BIOTECNOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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