USP22 regulates lipidome accumulation by stabilizing PPARÎ³ in hepatocellular carcinoma.

Ning, Zhen; Guo, Xin; Liu, Xiaolong; Lu, Chang; Wang, Aman; Wang, Xiaolin; Wang, Wen; Chen, Huan; Qin, Wangshu; Liu, Xinyu; Zhou, Lina; Ma, Chi; Du, Jian; Lin, Zhikun; Luo, Haifeng; Otkur, Wuxiyar; Qi, Huan; Chen, Di; Xia, Tian; Liu, Jiwei; Tan, Guang; Xu, Guowang; Piao, Hai-Long

Ning, Zhen; Guo, Xin; Liu, Xiaolong; Lu, Chang; Wang, Aman; Wang, Xiaolin; Wang, Wen; Chen, Huan; Qin, Wangshu; Liu, Xinyu; Zhou, Lina; Ma, Chi; Du, Jian; Lin, Zhikun; Luo, Haifeng; Otkur, Wuxiyar; Qi, Huan; Chen, Di; Xia, Tian; Liu, Jiwei; Tan, Guang; Xu, Guowang; Piao, Hai-Long.

Afiliação

Ning Z; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Guo X; The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116000, China.
Liu X; Liaoning Key Laboratory of Molecular Targeted Drugs in Hepatobiliary and Pancreatic Cancer, Dalian, 116000, China.
Lu C; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Wang A; The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116000, China.
Wang X; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Wang W; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Chen H; The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116000, China.
Qin W; The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116000, China.
Liu X; Liaoning Key Laboratory of Molecular Targeted Drugs in Hepatobiliary and Pancreatic Cancer, Dalian, 116000, China.
Zhou L; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Ma C; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Du J; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Lin Z; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Luo H; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Otkur W; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Qi H; The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116000, China.
Chen D; Liaoning Key Laboratory of Molecular Targeted Drugs in Hepatobiliary and Pancreatic Cancer, Dalian, 116000, China.
Xia T; The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116000, China.
Liu J; Liaoning Key Laboratory of Molecular Targeted Drugs in Hepatobiliary and Pancreatic Cancer, Dalian, 116000, China.
Tan G; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Xu G; The First Affiliated Hospital of Dalian Medical University, Dalian Medical University, Dalian, 116000, China.
Piao HL; Liaoning Key Laboratory of Molecular Targeted Drugs in Hepatobiliary and Pancreatic Cancer, Dalian, 116000, China.

Nat Commun ; 13(1): 2187, 2022 04 21.

Article em En | MEDLINE | ID: mdl-35449157

Assuntos

Carcinoma Hepatocelular; Neoplasias Hepáticas; ATP Citrato (pro-S)-Liase; Acetil-CoA Carboxilase/genética; Acetil-CoA Carboxilase/metabolismo; Carcinogênese/genética; Carcinoma Hepatocelular/metabolismo; Transformação Celular Neoplásica; Ácidos Graxos; Humanos; Lipidômica; Lipogênese/genética; Neoplasias Hepáticas/metabolismo; PPAR gama/genética; PPAR gama/metabolismo; Ubiquitina Tiolesterase/genética; Ubiquitina Tiolesterase/metabolismo

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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