Death by differentiation: CD4<sup>+</sup> T cells kick out suspicious stem cells.

Tomei, Sara; Audiger, Cindy; Naik, Shalin H

Death by differentiation: CD4⁺ T cells kick out suspicious stem cells.

Tomei, Sara; Audiger, Cindy; Naik, Shalin H.

Afiliação

Tomei S; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3052, Australia.
Audiger C; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3052, Australia.
Naik SH; Immunology Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC 3052, Australia. Electronic address: naik.s@wehi.edu.au.

Cell Stem Cell ; 29(5): 655-656, 2022 05 05.

Article em En | MEDLINE | ID: mdl-35523132

ABSTRACT

ABSTRACT

Antigen presentation is typically regarded as the domain of immune cells such as dendritic cells and B cells. Hernandez-Malmierca et al. (2022) upend this notion by observing that hematopoietic stem and progenitor cells process and present antigen via major histocompatibility class II as a means of CD4+ T cell-mediated immune surveillance.

Assuntos

Linfócitos T CD4-Positivos; Antígenos de Histocompatibilidade Classe II; Apresentação de Antígeno; Linfócitos B; Células Dendríticas; Células-Tronco

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Antígenos de Histocompatibilidade Classe II Idioma: En Revista: Cell Stem Cell Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Austrália

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