Sanguinarine, a major alkaloid from Zanthoxylum nitidum (Roxb.) DC., inhibits urease of Helicobacter pylori and jack bean: Susceptibility and mechanism.

Lu, Qiang; Zhang, Zhenshan; Xu, Yifei; Chen, Yujia; Li, Cailan

Lu, Qiang; Zhang, Zhenshan; Xu, Yifei; Chen, Yujia; Li, Cailan.

Afiliação

Lu Q; Department of Pharmaceutical Sciences, Zunyi Medical University, Zhuhai Campus, Zhuhai, 519041, PR China.
Zhang Z; Analysis & Test Center, Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, PR China.
Xu Y; Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, 518005, PR China.
Chen Y; Department of Pharmaceutical Sciences, Zunyi Medical University, Zhuhai Campus, Zhuhai, 519041, PR China.
Li C; Department of Pharmacology, Zunyi Medical University, Zhuhai Campus, Zhuhai, 519041, PR China; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, Guizhou, 563000, PR Chi

J Ethnopharmacol ; 295: 115388, 2022 Sep 15.

Article em En | MEDLINE | ID: mdl-35577159

Assuntos

Alcaloides; Helicobacter pylori; Zanthoxylum; Alcaloides/farmacologia; Benzofenantridinas; Canavalia; Glutationa/farmacologia; Isoquinolinas; Cinética; Compostos de Sulfidrila/química; Compostos de Sulfidrila/farmacologia; Urease

Palavras-chave

Helicobacter pylori urease; Inhibitor; Jack bean urease; Mechanism; Sanguinarine; Zanthoxylum nitidum

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Helicobacter pylori / Zanthoxylum / Alcaloides Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2022 Tipo de documento: Article

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